6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone

6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Suppliers list

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Products Intro:	Product Name:6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone CAS:179688-29-0

6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone manufacturers

6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Basic information

Product Name:	6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone
Synonyms:	6,7-BIS(2-METHOXYETHOXY)QUINAZOLIN-4(1H)-ONE;Erlotinib LactaM IMpurity;6,7-Bis(2-Methoxyethoxy)-3H-quinazolin-4-one;6,7-bis-Methoxyethoxy-quinazolin-4-one;Erlotinib iMpurity E;6,7-bis(2-methoxyethoxy)-1H-quinazolin-4-one;6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone;6,7-Bis-(2-Methoxyethoxy)quinazolin-4(3H)-one
CAS:	179688-29-0
MF:	C14H18N2O5
MW:	294.3
EINECS:	605-867-4
Product Categories:	Erlotinib INTERMEDIATES;intermidiate of Erlotinib hydrochloride;Erlotinib;Aromatics;Heterocycles;Intermediates;Aromatics Compounds;Intermediate of erlotinib hydrochloride
Mol File:	179688-29-0.mol

6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Chemical Properties

Melting point	185-189°C
Boiling point	467.8±55.0 °C(Predicted)
density	1.26±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO: ≥10mg/mL
pka	1.35±0.20(Predicted)
form	powder
color	off-white to light tan
InChI	InChI=1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
InChIKey	PMQWTUWLIGJTQD-UHFFFAOYSA-N
SMILES	N1C2=C(C=C(OCCOC)C(OCCOC)=C2)C(=O)NC=1
CAS DataBase Reference	179688-29-0(CAS DataBase Reference)

Safety Information

WGK Germany	3
HS Code	2933.59.8000

MSDS Information

6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Usage And Synthesis

Chemical Properties	Off-White Solid
Uses	An intermediate in the synthesis of Erlotinib (E625000).
Biological Activity	CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase th at activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Preparation Products And Raw materials

Preparation Products

Tag:6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone(179688-29-0) Related Product Information

Cefazolin sodium salt Quinoxaline Cefazolin 2-Amino-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester hydrochloride 3-Ethynylaniline Erlotinib hydrochloride 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Ethyl 3,4-dihydroxybenzoate 4-Quinazolinamine,N-(3-ethenylphenyl)-6,7-bis(2-methoxyethoxy)-,hydrochloride(1:1) Erlotinib Impurity 20 Erlotinib Impurity 1 Erlotinib Impurity 3 DesMethyl Erlotinib Carboxylate Acid Erlotinib Impurity 35 4-CHLORO-7-(2-CHLORO-ETHOXY)-6-(2-METHOXY-ETHOXY)-QUINAZOLINE Ethyl 3,4-bis(2-methoxyethoxy)benzoate Erlotinib Hydrochloride iMpurity