| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Imupedone
CAS:86187-86-2
Purity:99% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Imupedone
CAS:86187-86-2
Purity:99.09% Package:1mg/RMB 1980;5mg/RMB 4920;10mg/RMB 7130
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| Company Name: |
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| Tel: |
|
| Email: |
sangon@qq.com |
| Products Intro: |
Product Name:LF 1695, 10 mM in DMSO
CAS:86187-86-2
|
LF 1695 manufacturers
- Imupedone
-
- $293.00 / 1mg
-
2024-11-20
- CAS:86187-86-2
- Min. Order:
- Purity: 99.09%
- Supply Ability: 10g
|
| | LF 1695 Basic information |
| Product Name: | LF 1695 | | Synonyms: | LF 1695;[5-Amino-2-(4-methyl-1-piperidinyl)phenyl](4-chlorophenyl)methanone;5-Amino-4'-chloro-2-(4-methyl-1-piperidinyl)benzophenone;[2-(4-methyl-1-piperidinyl)-5-aminophenyl]-(4-chlorophenyl)-methanone;Imupedone;LF1695|||LF-1695|||LF 1695;LF 1695, 10 mM in DMSO | | CAS: | 86187-86-2 | | MF: | C19H21ClN2O | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 86187-86-2.mol |  |
| | LF 1695 Chemical Properties |
| | LF 1695 Usage And Synthesis |
| Description | LF 1695 is a synthetic immunomodulator. | | in vitro | This was further confirmed by the fact that LF 1695 inhibited the second wave of platelet aggregation induced by ADP as well as arachidonic acid effects. Incubation of platelets with [14C]arachidonic acid in the presence of 60 microM LF 1695 resulted in a strong inhibition of arachidonic acid incorporation into the various cell lipids, indicating that arachidonic acid mobilization might be due to inhibition of reacylation processes._x000D_
_x000D_
Reference: Biochem Pharmacol. 1989 Sep 1;38(17):2763-72. https://pubmed.ncbi.nlm.nih.gov/2505775/ | | in vivo | CBA, H2k mice receiving a lethal dose of irradiation were injected with spleen cells from LF 1695-treated or untreated C57 Bl/6, H2b mice via different routes. Mice treated intraperitoneally with LF 1695 at 2.5 or 5 mg/kg/day showed an increase of GvHR intensity with splenic index of 1.71 and 1.80, respectively. When the animals were treated continuously through drinking water containing LF 1695 (4 mg/kg, 10 mg/kg or 100 mg/kg), these ratios were: 1.82, 1.10 and 1.37, respectively. Finally, LF 1695 enhanced GvHR significantly when used at low doses, while high doses induced a decrease of GvHR intensity._x000D_
_x000D_
Reference: Int J Immunopharmacol. 1991;13(5):599-604. https://pubmed.ncbi.nlm.nih.gov/1838358/ | | target | LF 1695 is a synthetic immunomodulator. |
| | LF 1695 Preparation Products And Raw materials |
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