- Telbivudine
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- $0.00 / 1Kg/Bag
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2024-12-13
- CAS:3424-98-4
- Min. Order: 1KG
- Purity: 99.5%min
- Supply Ability: 10kg
- 2'-Deoxy-L-thymidine
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- $10.00 / 1KG
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2024-11-29
- CAS:3424-98-4
- Min. Order: 100KG
- Purity: 99%
- Supply Ability: 100 mt
- Telbivudine
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- $40.00 / 5mg
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2024-11-19
- CAS:3424-98-4
- Min. Order:
- Purity: 99.98%
- Supply Ability: 10g
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| | 2'-Deoxy-L-thymidine Basic information |
| Product Name: | 2'-Deoxy-L-thymidine | | Synonyms: | 2'-Deoxy-L-thyMidine(Telbivudine);Telbivudine(Tyzeka, Sebivo);1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-Methyl-;Telbivudine(L-ThyMidine,LDT-600);1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione;2,4(1H,3H)-PyriMidinedione,1-(2-deoxy-b-L-erythro-pentofuranosyl)-5-Methyl-;Sebivo;Telbivudine(L-ThyMidine) | | CAS: | 3424-98-4 | | MF: | C10H14N2O5 | | MW: | 242.23 | | EINECS: | 608-961-3 | | Product Categories: | Anti-virals;Bases & Related Reagents;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;API intermediates;Amines;API;Chiral Reagents;Heterocycles | | Mol File: | 3424-98-4.mol |  |
| | 2'-Deoxy-L-thymidine Chemical Properties |
| Melting point | 188-190°C | | alpha | D20 -20.3° (c = 0.192 in water) | | density | 1.452±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | H2O: soluble10mg/mL (clear solution) | | pka | 9.55±0.10(Predicted) | | form | powder | | color | white to beige | | optical activity | [α]/D -15 to -22°, c = 1 in H2O | | InChIKey | IQFYYKKMVGJFEH-CSMHCCOUSA-N |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | UV9048500 | | HS Code | 29349990 |
| | 2'-Deoxy-L-thymidine Usage And Synthesis |
| Description | Telbivudine is a b-L-thymidine nucleoside analog launched for the
once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is
the fourth nucleoside or nucleotide analog to be marketed for this indication. The
previous drugs from this class include lamivudine, a deoxythiacytosine analog,
adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir,
and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated
by cellular kinases to the active triphosphate derivative, which
inhibits HBV DNA polymerase by competing with the natural substrate, thymidine-
5’-triphosphate. | | Chemical Properties | 2'-Deoxy-L-thymidine is White Solid | | Originator | Idenix (US) | | Uses | Telbivudine(Tyzeka, Sebivo) is an antiviral drug used in the treatment of hepatitis B infection. Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Telbivudine is a synthetic | | Uses | Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral. | | Definition | ChEBI: A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase. | | Brand name | (Novirio). |
| | 2'-Deoxy-L-thymidine Preparation Products And Raw materials |
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