|
|
| | Kazinol U Basic information |
| Product Name: | Kazinol U | | Synonyms: | Kazinol U;4-[(2R)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol;1,2-Benzenediol, 4-[(2S)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)- | | CAS: | 1238116-48-7 | | MF: | C20H22O4 | | MW: | 326.39 | | EINECS: | | | Product Categories: | | | Mol File: | 1238116-48-7.mol |  |
| | Kazinol U Chemical Properties |
| Boiling point | 538.8±50.0 °C(Predicted) | | density | 1.243±0.06 g/cm3(Predicted) | | storage temp. | -10 to -25°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 9.72±0.40(Predicted) | | color | white to beige |
| | Kazinol U Usage And Synthesis |
| Biological Activity | Kazinol U is prenylated flavan isolated from an extract of Broussonetia kazinoki Sieb (paper mulberry) th at exhibits anti-melanogenic activity in mouse and human melanoma cells through the induction of AMPK and MAPK phosphorylation. Kazinol U inhibits tyrosinase activity and melanin synthesis through the reduction of MITF expression. It suppresses melanogenesis in a zebrafish model. Kazinol U displays phytoestrogenic and anti-inflammatory activities. Kazinol U exhibits cytoprotective activities against cytokine-induced apoptotic cell death. | | target | Estrogen receptor | NF-kB | IkB | NO | NOS | IFN-γ | IL Receptor | IKK | Progestogen receptor |
| | Kazinol U Preparation Products And Raw materials |
|