N-乙酰基-3-(硫代亞硝基)-DL-纈氨酸
| 中文名稱 | N-乙?；?3-(硫代亞硝基)-DL-纈氨酸 |
|---|---|
| 中文同義詞 | N-乙酰基-3-(亞硝基硫代)-纈氨酸;N-乙?；?3-(硫代亞硝基)-DL-纈氨酸;S-亞硝基-N-乙酰-DL-青霉胺;S-亞硝基N-乙?；?DL-青霉胺;S-亞硝基-N-乙?；?DL-青霉胺(SNAP);S-亞硝基-N-乙酰青霉胺P2021044023;庫倫法試液隔膜無隔膜式通用-陰陽極液共享;2-乙酰氨基-3-甲基-3-(硫代亞硝基)丁酸 |
| 英文名稱 | 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid |
| 英文同義詞 | N-(ACETYLOXY)-3-NITROSOTHIOVALINE;(+/-)-S-NITROSO-N-ACETYLPENICILLAMINE;S-Nitroso-N-acetyl-DL-penicillamine,N-Acetyl-3-(nitrosothio)-DL-valine, S-Nitroso-N-acetylpenicillamine, SNAP;(R)-2-acetaMido-3-Methyl-3-(nitrosothio)butanoic acid;SNAP [S-Nitroso-N-acetylpenicillaMine];Anti-SNAP25, C-Terminal antibody produced in rabbit;SNP25;SUP |
| CAS號 | 67776-06-1 |
| 分子式 | C7H12N2O4S |
| 分子量 | 220.25 |
| EINECS號 | |
| 相關(guān)類別 | 熒光探針，標(biāo)記，顆粒和染色;Signalling |
| Mol文件 | 67776-06-1.mol |
| 結(jié)構(gòu)式 |  |
N-乙?；?3-(硫代亞硝基)-DL-纈氨酸 性質(zhì)
| 熔點(diǎn) | 150.5°C |
|---|---|
| 密度 | 1.4261 (rough estimate) |
| 折射率 | 1.5400 (estimate) |
| RTECS號 | YV9383000 |
| 儲存條件 | -20°C |
| 溶解度 | H2O:≥2 mg/mL |
| 形態(tài) | 粉末 |
| 酸度系數(shù)(pKa) | 3.06±0.10(Predicted) |
| 顏色 | 綠色 |
| CAS 數(shù)據(jù)庫 | 67776-06-1(CAS DataBase Reference) |
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) 是一種一氧化氮供體，是一種穩(wěn)定的血小板聚集抑制劑。
S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) induces toxicity of about 80% after 6 hours under normoxic conditions by releasing nitric oxide (NO).
S-Nitroso-N-acetyl-DL-penicillamine has a half-time about 6 hours in in isolated rat ventricular myocytes.
S-Nitroso-N-acetyl-DL-penicillamine (100 μM; 30 minutes) causes sustained decrease in the basal pHi in isolated rat ventricular myocytes.
Cell Viability Assay
| Cell Line: | Rat liver sinusoidal endothelial cells |
| Concentration: | 2 mM, 5 mM, 10 mM |
| Incubation Time: | 2 hours, 4 hours, 6 hours, 8 hours |
| Result: | Exhibited cytotoxicity against cultivated endothelial cells. |
SNAP (100μM, 300μM) causes small but significant increases of the electrically evoked [
3
H]-acetylcholine release in guinea-pig tracheal.
| 提供商 | 語言 |
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英文
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| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2024/11/08 | HY-121526 | S-Nitroso-N-acetyl-DL-penicillamine | 5 mg | 333元 | |
| 2024/11/08 | HY-121526 | N-乙?；?3-(硫代亞硝基)-DL-纈氨酸 S-Nitroso-N-acetyl-DL-penicillamine | 67776-06-1 | 10mg | 500元 |
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