- 3-Amino-4-fluorophenol
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- $0.00 / 1KG
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2025-04-15
- CAS:62257-16-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- 3-Amino-4-fluorophenol
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- $15.00 / 1KG
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2021-08-12
- CAS:62257-16-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| 3-Amino-4-fluorophenol Basic information |
| 3-Amino-4-fluorophenol Chemical Properties |
Melting point | 141-143 °C | Boiling point | 269.3±20.0 °C(Predicted) | density | 1.347±0.06 g/cm3(Predicted) | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | pka | 10.03±0.18(Predicted) | form | crystalline powder | color | Light tan | InChI | InChI=1S/C6H6FNO/c7-5-2-1-4(9)3-6(5)8/h1-3,9H,8H2 | InChIKey | VJCSFNNTQGRAKH-UHFFFAOYSA-N | SMILES | C1(O)=CC=C(F)C(N)=C1 | CAS DataBase Reference | 62257-16-3(CAS DataBase Reference) |
Hazard Codes | Xn | Risk Statements | 22 | Hazard Note | Toxic | HS Code | 2922290090 |
| 3-Amino-4-fluorophenol Usage And Synthesis |
Description | 3-amino-4-fluorophenol is a kind of organic chemistry intermediate commonly used as the intermediate for synthesizing compounds of liquid crystals, pharmaceutical compounds and agricultural chemical compounds used always. | Uses |
3-Amino-4-fluorophenol is used to produce drugs with specific biological activities, including antibiotics and anti-inflammatory agents.
| Synthesis | Add 450ml water in the 5L reaction flask, 708.5g (10.9mol) zinc powder, 303g (1.09mol) 2-bromo-4-fluoro-5-amino-benzene oxygen ethyl formate, mix, 45 ℃ drip the solution that 218g (5.45mol) sodium hydroxide and 1500ml water are made into down, insulated and stirred is warming up to 60 ℃ after 1 hour to be incubated 4 hours after reactions more complete, the cooling suction filtration, getting filtrate dropping 406g (3.33mol) 30% hydrochloric acid separates product, filtration obtains brown solid, use ethyl alcohol recrystallization, get yellow solid 118.5g (0.93mol) 3-amino-4-fluorophenol after the drying. A molar yield of 85% is 99.5% through gas chromatography determination purity.136 ℃/20mmHg of boiling point.
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| 3-Amino-4-fluorophenol Preparation Products And Raw materials |
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