熒光專用試劑
中文名稱 | 熒光專用試劑 |
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中文同義詞 | 單溴代雙滿;溴代雙滿;溴二胺;熒光專用試劑;MBBR[單溴二胺];溴代雙滿,溴二胺,MONOBROMOBIMANE(MBBR );單溴二胺 MBBR;化合物 T18929 |
英文名稱 | MONOBROMOBIMANE |
英文同義詞 | MONOBROMOBIMANE;THIOLYTE MONOBROMOBIMANE REAGENT;THIOLYTE(R) MB;THIOLYTE(R) MB REAGENT;THIOLYTE(R) MONOBROMOBIMANE REAGENT;THIOLYTE(R) MONOBROMOBIMANE REAGENT, FLUORESCENT LABELING COMPOUND;MONOBROMOBIMANE, FOR FLUORESCENCE;BROMOBIMANE |
CAS號 | 71418-44-5 |
分子式 | C10H11BrN2O2 |
分子量 | 271.11 |
EINECS號 | |
相關(guān)類別 | 熒光探針,標(biāo)記,顆粒和染色;基準(zhǔn)試劑;Pyrazole;Fluorescent Labels and Indicators;Fluorescent Labels & Indicators;MTS & Sulfhydryl Active Reagents |
Mol文件 | 71418-44-5.mol |
結(jié)構(gòu)式 | ![]() |
熒光專用試劑 性質(zhì)
熔點(diǎn) | 152-154 °C(lit.) |
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沸點(diǎn) | 327.8±44.0 °C(Predicted) |
密度 | 1.66±0.1 g/cm3(Predicted) |
儲存條件 | 2-8°C |
溶解度 | 在DMF中可溶 |
酸度系數(shù)(pKa) | -3.36±0.70(Predicted) |
形態(tài) | 粉末 |
顏色 | 粘黃色 |
最大波長(λmax) | 398 nm |
ε(消光系數(shù)) | 4.6-5.1 at 396-398nm in H2O |
BRN | 4430959 |
穩(wěn)定性 | 感光 |
生物領(lǐng)域應(yīng)用 | Glutathione S-transferase substrates; detecting glutathione S-transferase,thiols,sulfite,homocysteine,mycothiol,sulfur compounds; thiol-reactive probes |
CAS 數(shù)據(jù)庫 | 71418-44-5 |
Bromobimanes in solution (aqueous or organic solvents of medium polarity) react with small thiols [e.g., the tripeptide thiol glutathione (GSH)], and with reactive protein thiol groups (e.g., hemoglobin). The reactions of bromobimanes with thiols are second order and dependent on pH, the active nucleophile being the thiolate anion. The reaction of bromobimane with a thiolate converts the nonfluorescent agent into water-soluble fluorescent products. The neutral agents mBBr and bBBr are moderately soluble in mediumpolarity organic solvents (acetonitrile, dichloromethane), and slightly soluble in water. The quaternary salt, qBBr, and the anionic bromobimane, SBBr, are soluble in water, but less soluble in organic solvents. Bromobimanes are yellow. The highly selective, rapid reactivity of bromobimanes toward thiols, the stability and fluorescence yield of the thiol derivatives, the ease of separation of the derivatives by reversed-phase HPLC, and the availability of both cell-penetrating and nonpenetrating forms, make the use bromobimanes an extremely powerful approach to the analysis of low molecular weight biothiols.
提供商 | 語言 |
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英文
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更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
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2025/05/22 | B4220 | 溴代雙滿 Bromobimane | 71418-44-5 | 20mg | 1330元 |
2025/05/22 | B4220 | 溴代雙滿 Bromobimane | 71418-44-5 | 100mg | 3990元 |