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熒光專用試劑

熒光專用試劑

中文名稱熒光專用試劑
中文同義詞單溴代雙滿;溴代雙滿;溴二胺;熒光專用試劑;MBBR[單溴二胺];溴代雙滿,溴二胺,MONOBROMOBIMANE(MBBR );單溴二胺 MBBR;化合物 T18929
英文名稱MONOBROMOBIMANE
英文同義詞MONOBROMOBIMANE;THIOLYTE MONOBROMOBIMANE REAGENT;THIOLYTE(R) MB;THIOLYTE(R) MB REAGENT;THIOLYTE(R) MONOBROMOBIMANE REAGENT;THIOLYTE(R) MONOBROMOBIMANE REAGENT, FLUORESCENT LABELING COMPOUND;MONOBROMOBIMANE, FOR FLUORESCENCE;BROMOBIMANE
CAS號71418-44-5
分子式C10H11BrN2O2
分子量271.11
EINECS號
相關(guān)類別熒光探針,標(biāo)記,顆粒和染色;基準(zhǔn)試劑;Pyrazole;Fluorescent Labels and Indicators;Fluorescent Labels & Indicators;MTS & Sulfhydryl Active Reagents
Mol文件71418-44-5.mol
結(jié)構(gòu)式熒光專用試劑 結(jié)構(gòu)式

熒光專用試劑 性質(zhì)

熔點(diǎn)152-154 °C(lit.)
沸點(diǎn)327.8±44.0 °C(Predicted)
密度1.66±0.1 g/cm3(Predicted)
儲存條件2-8°C
溶解度在DMF中可溶
酸度系數(shù)(pKa)-3.36±0.70(Predicted)
形態(tài)粉末
顏色粘黃色
最大波長(λmax)398 nm
ε(消光系數(shù))4.6-5.1 at 396-398nm in H2O
BRN4430959
穩(wěn)定性感光
生物領(lǐng)域應(yīng)用Glutathione S-transferase substrates; detecting glutathione S-transferase,thiols,sulfite,homocysteine,mycothiol,sulfur compounds; thiol-reactive probes
CAS 數(shù)據(jù)庫71418-44-5

熒光專用試劑 用途與合成方法

Bromobimane基本上是非熒光物質(zhì),當(dāng)與小硫醇反應(yīng)時,生成熒光產(chǎn)物。

Bromobimanes in solution (aqueous or organic solvents of medium polarity) react with small thiols [e.g., the tripeptide thiol glutathione (GSH)], and with reactive protein thiol groups (e.g., hemoglobin). The reactions of bromobimanes with thiols are second order and dependent on pH, the active nucleophile being the thiolate anion. The reaction of bromobimane with a thiolate converts the nonfluorescent agent into water-soluble fluorescent products. The neutral agents mBBr and bBBr are moderately soluble in mediumpolarity organic solvents (acetonitrile, dichloromethane), and slightly soluble in water. The quaternary salt, qBBr, and the anionic bromobimane, SBBr, are soluble in water, but less soluble in organic solvents. Bromobimanes are yellow. The highly selective, rapid reactivity of bromobimanes toward thiols, the stability and fluorescence yield of the thiol derivatives, the ease of separation of the derivatives by reversed-phase HPLC, and the availability of both cell-penetrating and nonpenetrating forms, make the use bromobimanes an extremely powerful approach to the analysis of low molecular weight biothiols.

安全信息

安全說明22-24/25
WGK Germany3
F8
海關(guān)編碼2933.99.8290

MSDS信息

提供商 語言
英文
更新日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2025/05/22B4220溴代雙滿
Bromobimane
71418-44-520mg1330元
2025/05/22B4220溴代雙滿
Bromobimane
71418-44-5100mg3990元

熒光專用試劑 上下游產(chǎn)品信息

"熒光專用試劑"相關(guān)產(chǎn)品信息
熒光素二乙酸鹽 Dibenzocyclooctyne-Cy5 熒光素酶 熒光素二(BETA-D-吡喃半乳糖苷) 熒光素二辛酸鹽 熒光素5-馬來酰亞胺 熒光素鈉 熒光染料OG488DHPE 熒光素二辛酸鹽WS1 熒光增白劑71 熒光染料FORTEBLUEDHPE 熒光探針WSP-1 熒光素 FLUORESCEINDHPE 熒光染料TRITC-DHPE 熒光染料TEXASRED-DHPE 二烯丙基胺 1-溴-2-丁烯
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