ABT-888
2物価
選択條件:
ブランド
- 富士フイルム和光純薬株式會(huì)社(wako)
パッケージ
- 1mg
- 5mg
- 生産者富士フイルム和光純薬株式會(huì)社(wako)
- 製品番號(hào)W01BVI1620-5
- 製品説明
- 英語(yǔ)製品説明ABT-888
- 包裝単位5mg
- 価格¥135200
- 更新しました2020-09-21
- 購(gòu)入
- 生産者富士フイルム和光純薬株式會(huì)社(wako)
- 製品番號(hào)W01BVI1620-1
- 製品説明
- 英語(yǔ)製品説明ABT-888
- 包裝単位1mg
- 価格¥40300
- 更新しました2020-09-21
- 購(gòu)入
生産者 | 製品番號(hào) | 製品説明 | 包裝単位 | 価格 | 更新時(shí)間 | 購(gòu)入 |
---|---|---|---|---|---|---|
富士フイルム和光純薬株式會(huì)社(wako) | W01BVI1620-5 | ABT-888 |
5mg | ¥135200 | 2020-09-21 | 購(gòu)入 |
富士フイルム和光純薬株式會(huì)社(wako) | W01BVI1620-1 | ABT-888 |
1mg | ¥40300 | 2020-09-21 | 購(gòu)入 |
プロパティ
融點(diǎn) :>173°C (dec.)
貯蔵溫度 :Refrigerator
溶解性 :Methanol (Slightly, Heated), THF (Slightly, Heated)
外見 :Colorless to white crystalline solid.
色 :Off-White to Dark Yellow
貯蔵溫度 :Refrigerator
溶解性 :Methanol (Slightly, Heated), THF (Slightly, Heated)
外見 :Colorless to white crystalline solid.
色 :Off-White to Dark Yellow
安全情報(bào)
絵表示(GHS): | ||||||||||||||||||||||
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注意喚起語(yǔ): | Warning | |||||||||||||||||||||
危険有害性情報(bào): |
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注意書き: |
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説明
Poly(ADP-ribose) polymerases (PARPs) have diverse roles in cellular processes, including DNA repair and apoptosis. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). It enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). It enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 also acts synergistically with chemotherapies to increase the lethal effects of radiation in cancer cells.関連商品価格
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