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ChemicalBook >> CAS DataBase List >> ABT-888

ABT-888

ABT-888 price.
  • $44 - $1980
  • Product name: ABT-888
  • CAS: 912445-05-7
  • MF: C13H16N4O
  • MW: 244.296
  • EINECS:1592732-453-0
  • MDL Number:MFCD12407402
  • Synonyms:ABT-888;2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide,dihydrochloridesalt;2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride;Veliparib dihydrochloride;ABT-888(Veliparib dihydrochloride);ABT-888 dihydrochloride;ABT888 HCl;Veliparib hydrochloride
27 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Tocris
Package
  • 1mg
  • 5MG
  • 10mg
  • 50
  • 2x10mg
  • 25MG
  • 50mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5722
  • Product descriptionABT-888
  • Packaging50mg
  • Price$547
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000299
  • Product description2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$724.19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000299
  • Product description2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$1000.52
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3958
  • Product descriptionVeliparibdihydrochloride
  • Packaging10mM(in 1mL DMSO)
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3958
  • Product descriptionVeliparibdihydrochloride
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3958
  • Product descriptionVeliparibdihydrochloride
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3958
  • Product descriptionVeliparibdihydrochloride
  • Packaging50mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3958
  • Product descriptionVeliparibdihydrochloride
  • Packaging200mg
  • Price$678
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2888
  • Product descriptionABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99%
  • Packaging2x10mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2888
  • Product descriptionABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99%
  • Packaging50mg
  • Price$313.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11505
  • Product descriptionABT-888 (hydrochloride) ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11505
  • Product descriptionABT-888 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11505
  • Product descriptionABT-888 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11505
  • Product descriptionABT-888 (hydrochloride) ≥98%
  • Packaging25mg
  • Price$267
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0077
  • Product descriptionVeliparibdihydrochloride 99.96%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0077
  • Product descriptionVeliparibdihydrochloride 99.96%
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5722 ABT-888 50mg $547 2021-12-16 Buy
American Custom Chemicals Corporation INB0000299 2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00% 5MG $724.19 2021-12-16 Buy
American Custom Chemicals Corporation INB0000299 2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00% 25MG $1000.52 2021-12-16 Buy
ApexBio Technology A3958 Veliparibdihydrochloride 10mM(in 1mL DMSO) $57 2021-12-16 Buy
ApexBio Technology A3958 Veliparibdihydrochloride 5mg $65 2021-12-16 Buy
ApexBio Technology A3958 Veliparibdihydrochloride 10mg $85 2021-12-16 Buy
ApexBio Technology A3958 Veliparibdihydrochloride 50mg $260 2021-12-16 Buy
ApexBio Technology A3958 Veliparibdihydrochloride 200mg $678 2021-12-16 Buy
Axon Medchem Axon2888 ABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99% 2x10mg $154 2021-12-16 Buy
Axon Medchem Axon2888 ABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99% 50mg $313.5 2021-12-16 Buy
Cayman Chemical 11505 ABT-888 (hydrochloride) ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 11505 ABT-888 (hydrochloride) ≥98% 5mg $109 2024-03-01 Buy
Cayman Chemical 11505 ABT-888 (hydrochloride) ≥98% 10mg $142 2024-03-01 Buy
Cayman Chemical 11505 ABT-888 (hydrochloride) ≥98% 25mg $267 2024-03-01 Buy
ChemScene CS-0077 Veliparibdihydrochloride 99.96% 5mg $60 2021-12-16 Buy
ChemScene CS-0077 Veliparibdihydrochloride 99.96% 10mg $84 2021-12-16 Buy

Properties

Melting point :>173°C (dec.)
storage temp. :Refrigerator
solubility :Methanol (Slightly, Heated), THF (Slightly, Heated)
form :Colorless to white crystalline solid.
color :Off-White to Dark Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Poly(ADP-ribose) polymerases (PARPs) have diverse roles in cellular processes, including DNA repair and apoptosis. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). It enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). It enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 also acts synergistically with chemotherapies to increase the lethal effects of radiation in cancer cells.

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