Tie2 kinase inhibitor
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- $40 - $1125
- Product name: Tie2 kinase inhibitor
- CAS: 948557-43-5
- MF: C26H21N3O2S
- MW: 439.53
- EINECS:
- MDL Number:MFCD14585804
- Synonyms:Tie2 kinase inhibitor;4-[4-(6-Methoxy-2-naphthalenyl)-2-[4-(Methylsulfinyl)phenyl]-1H-iMidazol-5-yl]pyridine;4-(6-Methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole;4-(5-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)pyridine;Tie2 kinase-IN-1;Tie2 kinase inhibitor 1;4-(4-(6-Methoxynaphthalen-2-yl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine;Pyridine, 4-[4-(6-methoxy-2-naphthalenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-
16 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Crysdot
- CSNpharm
- TRC
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number2758AH
- Product descriptionTie2KinaseInhibitor
- Packaging250mg
- Price$1125
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA253059
- Product descriptionTie2kinase-IN-1 98+%
- Packaging10mg
- Price$101
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA253059
- Product descriptionTie2kinase-IN-1 98+%
- Packaging50mg
- Price$256
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA253059
- Product descriptionTie2kinase-IN-1 98+%
- Packaging100mg
- Price$384
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5979
- Product descriptionTie2kinaseinhibitor
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17858
- Product descriptionTie2 Kinase Inhibitor ≥95%
- Packaging500μg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17858
- Product descriptionTie2 Kinase Inhibitor ≥95%
- Packaging1mg
- Price$64
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17858
- Product descriptionTie2 Kinase Inhibitor ≥95%
- Packaging5mg
- Price$195
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17858
- Product descriptionTie2 Kinase Inhibitor ≥95%
- Packaging10mg
- Price$351
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM330047
- Product descriptionTie2kinaseinhibitor1 95%+
- Packaging100mg
- Price$819
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11005643
- Product descriptionTie2KinaseInhibitor 95+%
- Packaging10mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11005643
- Product descriptionTie2KinaseInhibitor 95+%
- Packaging50mg
- Price$315
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11005643
- Product descriptionTie2KinaseInhibitor 95+%
- Packaging100mg
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN16555
- Product descriptionTie2kinase-IN-1
- Packaging10mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN16555
- Product descriptionTie2kinase-IN-1
- Packaging100mg
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM264745
- Product description4-(6-Methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole
- Packaging10mg
- Price$295
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2758AH | Tie2KinaseInhibitor | 250mg | $1125 | 2021-12-16 | Buy |
| Ambeed | A253059 | Tie2kinase-IN-1 98+% | 10mg | $101 | 2021-12-16 | Buy |
| Ambeed | A253059 | Tie2kinase-IN-1 98+% | 50mg | $256 | 2021-12-16 | Buy |
| Ambeed | A253059 | Tie2kinase-IN-1 98+% | 100mg | $384 | 2021-12-16 | Buy |
| ApexBio Technology | A5979 | Tie2kinaseinhibitor | 5mg | $100 | 2021-12-16 | Buy |
| Cayman Chemical | 17858 | Tie2 Kinase Inhibitor ≥95% | 500μg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 17858 | Tie2 Kinase Inhibitor ≥95% | 1mg | $64 | 2024-03-01 | Buy |
| Cayman Chemical | 17858 | Tie2 Kinase Inhibitor ≥95% | 5mg | $195 | 2024-03-01 | Buy |
| Cayman Chemical | 17858 | Tie2 Kinase Inhibitor ≥95% | 10mg | $351 | 2024-03-01 | Buy |
| Chemenu | CM330047 | Tie2kinaseinhibitor1 95%+ | 100mg | $819 | 2021-12-16 | Buy |
| Crysdot | CD11005643 | Tie2KinaseInhibitor 95+% | 10mg | $112 | 2021-12-16 | Buy |
| Crysdot | CD11005643 | Tie2KinaseInhibitor 95+% | 50mg | $315 | 2021-12-16 | Buy |
| Crysdot | CD11005643 | Tie2KinaseInhibitor 95+% | 100mg | $525 | 2021-12-16 | Buy |
| CSNpharm | CSN16555 | Tie2kinase-IN-1 | 10mg | $112 | 2021-12-16 | Buy |
| CSNpharm | CSN16555 | Tie2kinase-IN-1 | 100mg | $525 | 2021-12-16 | Buy |
| TRC | M264745 | 4-(6-Methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole | 10mg | $295 | 2021-12-16 | Buy |
Properties
Boiling point :699.8±55.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :≥22 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Powder
pka :9.53±0.10(Predicted)
color :Light yellow to yellow
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :≥22 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Powder
pka :9.53±0.10(Predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Tunica interna endothelial cell kinase 2 (Tie2, also known as angiopoietin-1 receptor or tek) is an endothelium-specific receptor tyrosine kinase important for the development of embryonic vasculature and for angiogenesis and vascular maintenance in adult tissues. Tie2 kinase inhibitor reversibly and selectively blocks Tie2 kinase activity with an IC50 value of 250 nM. It is 200-fold more potent for inhibition of Tie2 compared to p38. Tie2 kinase inhibitor has been shown to reduce angiogenesis in a Matrigel neovascularization assay and to delay tumor growth in MOPC-315 plasmacytoma and SVR angiosarcoma xenograft models.More related product prices
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