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ChemicalBook >> CAS DataBase List >> RP107

RP107

RP107 price.
  • $65 - $1963.5
  • Product name: RP107
  • CAS: 496864-16-5
  • MF: C16H17N3O
  • MW: 267.33
  • EINECS:
  • MDL Number:MFCD04973541
  • Synonyms:RP107;4-(7-BUTYL-5H-PYRROLO[2,3-B]PYRAZIN-6-YL)-PHENOL;ALOISINE A;ALOISINE A RP107;7-N-BUTYL-6-(4-HYDROXPHENYL)[5H]PYRROLO[2,3-B]PYRAZINE;7-N-BUTYL-6-(4-HYDROXYPHENYL)-[5H]PYRROLO[2,3-B]PYRAZINE;RP107, 7-n-Butyl-6-(4-hydroxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine;RP107, 7-n-Butyl-6-(4-hydroxyphenyl)-[5H]pyrrolo[2,3-β]pyrazine
13 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Chemenu
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10MG
  • 25mg
  • 100MG
  • 1g
  • ManufacturerAK Scientific
  • Product number3074CC
  • Product description4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol
  • Packaging5mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0097227
  • Product description4-(7-BUTYL-5H-PYRROLO[2,3-B]PYRAZIN-6-YL)PHENOL 95.00%
  • Packaging10MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0097227
  • Product description4-(7-BUTYL-5H-PYRROLO[2,3-B]PYRAZIN-6-YL)PHENOL 95.00%
  • Packaging100MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17320
  • Product descriptionAloisine A RP107
  • Packaging1mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17320
  • Product descriptionAloisine A RP107
  • Packaging2mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17320
  • Product descriptionAloisine A RP107
  • Packaging5mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17320
  • Product descriptionAloisine A RP107
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17320
  • Product descriptionAloisine A RP107
  • Packaging25mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM168068
  • Product description4-(7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol 95%
  • Packaging1g
  • Price$1232
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11116487
  • Product description4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol 95+%
  • Packaging1g
  • Price$1307
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number6319
  • Product descriptionAloisineARP107
  • Packaging10mg
  • Price$875
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number128125
  • Product descriptionAloisine A - CAS 496864-16-5 - Calbiochem
    A cell-permeable pyrrolo-pyrazine compound that exerts anti-proliferative effects.
  • Packaging5mg
  • Price$187
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA575450
  • Product descriptionAloisineARP107
  • Packaging100mg
  • Price$1175
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3074CC 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol 5mg $320 2021-12-16 Buy
American Custom Chemicals Corporation CHM0097227 4-(7-BUTYL-5H-PYRROLO[2,3-B]PYRAZIN-6-YL)PHENOL 95.00% 10MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation CHM0097227 4-(7-BUTYL-5H-PYRROLO[2,3-B]PYRAZIN-6-YL)PHENOL 95.00% 100MG $1963.5 2021-12-16 Buy
Biosynth Carbosynth FA17320 Aloisine A RP107 1mg $65 2021-12-16 Buy
Biosynth Carbosynth FA17320 Aloisine A RP107 2mg $100 2021-12-16 Buy
Biosynth Carbosynth FA17320 Aloisine A RP107 5mg $200 2021-12-16 Buy
Biosynth Carbosynth FA17320 Aloisine A RP107 10mg $300 2021-12-16 Buy
Biosynth Carbosynth FA17320 Aloisine A RP107 25mg $700 2021-12-16 Buy
Chemenu CM168068 4-(7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol 95% 1g $1232 2021-12-16 Buy
Crysdot CD11116487 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol 95+% 1g $1307 2021-12-16 Buy
Medical Isotopes, Inc. 6319 AloisineARP107 10mg $875 2021-12-16 Buy
Sigma-Aldrich 128125 Aloisine A - CAS 496864-16-5 - Calbiochem
A cell-permeable pyrrolo-pyrazine compound that exerts anti-proliferative effects. 		5mg $187 2024-03-01 Buy
TRC A575450 AloisineARP107 100mg $1175 2021-12-16 Buy

Properties

Melting point :281-283°C
Density :1.227
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Yellow solid
pka :9.67±0.15(Predicted)
color :Light Orangish Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Aloisine A is a cell permeable, potent, selective, reversible, and ATP-competitive inhibitor of Cdc2 (CDK1)/cyclin B (IC50 = 150nM), Cdk2/cyclin A (IC50 = 120nM), Cdk2/cyclin E (IC50 = 400nM), Cdk5/p25 (IC50 = 200nM), Cdk5/p35 (IC50 = 160nM), and GSK-3α (IC50 = 500nM). Aloisine A also inhibits GSK-3β (IC50 = 650nM) and JNK (c-Jun N-terminal kinase) (IC50~3-10μM). Aloisine A is a poor inhibitor of CK1, CK2, Cdk4/cyclin D1, MAPKK, PKA, PKG, PKCs and c-raf (IC50 ≥ 100μM). Aloisine A blocks the cell cycle in both G1 and G2 phase. Aloisine A is an activator of CFTR.

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