Empagliflozin
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- $5 - $1950
- Product name: Empagliflozin
- CAS: 864070-44-0
- MF: C23H27ClO7
- MW: 450.91
- EINECS:620-176-8
- MDL Number:MFCD22566222
- Synonyms:EMPAGLIFLBZIN;EMpagliflozin;BI-10773;EMpagliflozin/ BI-10773;D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]M ethyl]phenyl]-, (1S)-;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol Empagliflozin BI 10773;Empagliflozin Impurity A;(1S)-1,5-Anhydro-1-C-{4-chloro-3-[(4-{[(3S)-oxolan-3-yl]oxy}phenyl)methyl]phenyl}-D-glucitol
42 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
Package
- 10mg
- 10mM(in 1mL DMSO)
- 5MG
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 5g
- 10g
- 25g
- 100g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3619-M010
- Product descriptionEmpagliflozin ≥98%(HPLC)
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3619-M050
- Product descriptionEmpagliflozin ≥98%(HPLC)
- Packaging50mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX5927
- Product descriptionEmpagliflozin
- Packaging10g
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging10mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging50mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging100mg
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging250mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging1g
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging5g
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging10g
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging25g
- Price$277
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112500
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+%
- Packaging100g
- Price$748
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0046689
- Product descriptionEMPAGLIFLOZIN 95.00%
- Packaging5MG
- Price$459.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4601
- Product descriptionEmpagliflozin(BI10773)
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY046855
- Product description(2S,3R,4R,5S,6R)-2-[4-Chloro-3-[4-[[(S)-3-tetrahydrofuranyl]oxy]benzyl]phenyl]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
- Packaging10g
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3361
- Product descriptionEmpagliflozin
- Packaging10mg
- Price$29
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3619-M010 | Empagliflozin ≥98%(HPLC) | 10mg | $70 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3619-M050 | Empagliflozin ≥98%(HPLC) | 50mg | $180 | 2021-12-16 | Buy |
| AK Scientific | X5927 | Empagliflozin | 10g | $187 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 10mg | $5 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 50mg | $6 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 100mg | $9 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 250mg | $14 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 1g | $34 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 5g | $89 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 10g | $139 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 25g | $277 | 2021-12-16 | Buy |
| Ambeed | A112500 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 98+% | 100g | $748 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0046689 | EMPAGLIFLOZIN 95.00% | 5MG | $459.45 | 2021-12-16 | Buy |
| ApexBio Technology | A4601 | Empagliflozin(BI10773) | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| Arctom | SY046855 | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[4-[[(S)-3-tetrahydrofuranyl]oxy]benzyl]phenyl]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol | 10g | $165 | 2021-12-16 | Buy |
| AvaChem | 3361 | Empagliflozin | 10mg | $29 | 2021-12-16 | Buy |
Properties
Boiling point :665℃
Density :1.398
Flash point :356℃
storage temp. :2-8°C
solubility :insoluble in H2O; ≥20.75 mg/mL in DMSO; ≥7.06 mg/mL in EtOH with ultrasonic
form :solid
pka :13.23±0.70(Predicted)
color :White
Stability :Hygroscopic
InChIKey :OBWASQILIWPZMG-QZMOQZSNSA-N
SMILES :C1=C(CC2=CC([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=CC=C2Cl)C=CC(O[C@H]2CCOC2)=C1
Density :1.398
Flash point :356℃
storage temp. :2-8°C
solubility :insoluble in H2O; ≥20.75 mg/mL in DMSO; ≥7.06 mg/mL in EtOH with ultrasonic
form :solid
pka :13.23±0.70(Predicted)
color :White
Stability :Hygroscopic
InChIKey :OBWASQILIWPZMG-QZMOQZSNSA-N
SMILES :C1=C(CC2=CC([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=CC=C2Cl)C=CC(O[C@H]2CCOC2)=C1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||
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Description
Empagliflozin(trade name Jardiance) is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), and causes sugar in the blood to be excreted by the kidneys and eliminated in urine. On August 1, 2014, the Food and Drug Administration (FDA) officially approved the drug for the treatment of type 2 diabetes, to improve and control blood glucose of adults. Empagliflozin is the third SGLT-2 inhibiting drugs approved by FDA. Another two SGLT-2 inhibitor drugs, canagliflozin and dapagliflozin, belonging to Johnson Pharmaceuticals, AstraZeneca and Bristol-Myers Squibb respectively, are approved by FDA in November 2013 and January 2014 respectively. The new drug Empagliflozin’s application to FDA can be described as twists and turns. In March 2014, due to a large particle contamination incident at the empagliflozin production plant in Boehringer, the application of new drug submitted by the Boehringer-Eli Lilly Alliance was rejected by FDA. In June 2014, after reviewing the summary and material submitted by Boehring in March, confirming that the quality management and compliance system of the Boehring drug production facility was acceptable, FDA withdrew the previously issued warning letter. The Boehringer-Eli Lilly Alliance also filed an application with the FDA on June 17th.More related product prices
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