LX-4211
- $37 - $1700
- Product name: LX-4211
- CAS: 1018899-04-1
- MF: C21H25ClO5S
- MW: 424.94
- EINECS:
- MDL Number:MFCD22493506
- Synonyms:LX-4211;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(Methylthio)tetrahydro-2H-pyran-3,4,5-triol;(5S)-Methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-1-thio-beta-L-xylopyranoside;LX4211/LX-4211;LP 802034;LX4211 - L10525;LX-4211 (sotagliflozin);LX-4211, >=98%
18 prices
Selected condition:
Brand
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- 5g
- 100g
- 250g
- 500g
- ManufacturerApexBio Technology
- Product numberA3567
- Product descriptionLX-4211
- Packaging5mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBL161424
- Product descriptionLX4211
- Packaging25mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBL161424
- Product descriptionLX4211
- Packaging50mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBL161424
- Product descriptionLX4211
- Packaging100g
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBL161424
- Product descriptionLX4211
- Packaging250g
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBL161424
- Product descriptionLX4211
- Packaging500g
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19141
- Product descriptionSotagliflozin ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19141
- Product descriptionSotagliflozin ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19141
- Product descriptionSotagliflozin ≥98%
- Packaging10mg
- Price$283
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19141
- Product descriptionSotagliflozin ≥98%
- Packaging25mg
- Price$573
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM105513
- Product descriptionsotagliflozin 97%
- Packaging1g
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM105513
- Product descriptionsotagliflozin 97%
- Packaging5g
- Price$1650
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1069
- Product descriptionSotagliflozin 99.99%
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1069
- Product descriptionSotagliflozin 99.99%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1069
- Product descriptionSotagliflozin 99.99%
- Packaging25mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1069
- Product descriptionSotagliflozin 99.99%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
ApexBio Technology | A3567 | LX-4211 | 5mg | $165 | 2021-12-16 | Buy |
Biosynth Carbosynth | BL161424 | LX4211 | 25mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | BL161424 | LX4211 | 50mg | $100 | 2021-12-16 | Buy |
Biosynth Carbosynth | BL161424 | LX4211 | 100g | $150 | 2021-12-16 | Buy |
Biosynth Carbosynth | BL161424 | LX4211 | 250g | $300 | 2021-12-16 | Buy |
Biosynth Carbosynth | BL161424 | LX4211 | 500g | $500 | 2021-12-16 | Buy |
Cayman Chemical | 19141 | Sotagliflozin ≥98% | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 19141 | Sotagliflozin ≥98% | 5mg | $161 | 2024-03-01 | Buy |
Cayman Chemical | 19141 | Sotagliflozin ≥98% | 10mg | $283 | 2024-03-01 | Buy |
Cayman Chemical | 19141 | Sotagliflozin ≥98% | 25mg | $573 | 2024-03-01 | Buy |
Chemenu | CM105513 | sotagliflozin 97% | 1g | $550 | 2021-12-16 | Buy |
Chemenu | CM105513 | sotagliflozin 97% | 5g | $1650 | 2021-12-16 | Buy |
ChemScene | CS-1069 | Sotagliflozin 99.99% | 5mg | $100 | 2021-12-16 | Buy |
ChemScene | CS-1069 | Sotagliflozin 99.99% | 10mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-1069 | Sotagliflozin 99.99% | 25mg | $290 | 2021-12-16 | Buy |
ChemScene | CS-1069 | Sotagliflozin 99.99% | 50mg | $450 | 2021-12-16 | Buy |
Properties
Boiling point :607.9±55.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:84.0(Max Conc. mg/mL);197.67(Max Conc. mM)
Ethanol:17.0(Max Conc. mg/mL);40.01(Max Conc. mM) pka :12.87±0.70(Predicted)
form :Powder
color :White to off-white
InChIKey :QKDRXGFQVGOQKS-WFCPIQDQNA-N
SMILES :[C@@H]1(C2=CC=C(Cl)C(CC3=CC=C(OCC)C=C3)=C2)O[C@H](SC)[C@@H](O)[C@H](O)[C@H]1O |&1:0,19,22,24,26,r|
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:84.0(Max Conc. mg/mL);197.67(Max Conc. mM)
Ethanol:17.0(Max Conc. mg/mL);40.01(Max Conc. mM) pka :12.87±0.70(Predicted)
form :Powder
color :White to off-white
InChIKey :QKDRXGFQVGOQKS-WFCPIQDQNA-N
SMILES :[C@@H]1(C2=CC=C(Cl)C(CC3=CC=C(OCC)C=C3)=C2)O[C@H](SC)[C@@H](O)[C@H](O)[C@H]1O |&1:0,19,22,24,26,r|
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Inhibiting renal glucose reabsorption through the sodium-glucose cotransporter (SGLT) offers an insulin-independent alternative to controlling blood glucose concentrations in patients with type 2 diabetes. While the majority of glucose is reabsorbed from glomerular filtrate by SGLT2, which is predominantly expressed in the kidney S1 segment of the proximal tubule, SGLT1 reabsorbs glucose in the distal S3 segment of the renal proximal tubule as well as from the small intestine. Sotagliflozin is an orally available L-xyloside that potently inhibits both SGLT1 and SGLT2 (IC50s = 36 and 1.8 nM, respectively, for human isoforms in vitro). It improves glycemic control in nonobese diabetes prone mice with type 1 diabetes and in patients with type 2 diabetes in a randomized, placebo-controlled clinical trial. Sotagliflozin also increases serum glucagon-like peptide 1 and peptide YY levels by reducing SGLT1-mediated absorption of intestinal glucose.Related product price
- Canagliflozin
$5-4600 - (1S)-1,5-Anhydro-1-C-[3-[(1-benzothiophen-2-yl)methyl]-4-fluorophenyl]-D-glucitol
$32-9200 - Tofogliflozin
$375-18005
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED