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ChemicalBook >> CAS DataBase List >> Calcitriol

Calcitriol

Calcitriol price.
  • $64 - $6980
  • Product name: Calcitriol
  • CAS: 32222-06-3
  • MF: C27H44O3
  • MW: 416.64
  • EINECS:250-963-8
  • MDL Number:MFCD00867079
  • Synonyms:VITAMIN D3, 1ALPHA,25-DIHYDROXY;(5z,7e)-(1s,3r)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol;1,25-(OH)2-D3;(1ALPHA,3BETA,5Z,7E)-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL;1ALPHA,25-DIHYDROXYCHOLECALCIFEROL;1ALPHA,25-DIHYDROXYVITAMIN D3;1ALPHA,25-DIHYDROXY-VITAMIN D8;1A, 25-DIHYDROXYCHOLECALCIFEROL
53 prices
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Brand
  • AHH
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
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  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Chemtos
  • CSNpharm
  • DC Chemicals
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Package
  • 10μG
  • 50μg
  • 100μg
  • 0.1MG
  • 2mg
  • 1mL(100ug/mL)
  • 1mg
  • 5mg
  • 10mg
  • 2.5mg
  • c0225000
  • 25mg
  • 50mg
  • 50U
  • 100mg
  • 0.1g
  • 250mg
  • 10mM(in 1mL DMSO)
  • 500mg
  • 1mL
  • 1g
  • 5ml
  • ManufacturerAHH
  • Product numberAPI-1440
  • Product descriptionCalcitriol 98%
  • Packaging0.1g
  • Price$6980
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132740
  • Product description(1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+%
  • Packaging2mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132740
  • Product description(1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+%
  • Packaging5mg
  • Price$188
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132740
  • Product description(1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+%
  • Packaging10mg
  • Price$261
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132740
  • Product description(1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+%
  • Packaging50mg
  • Price$376
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132740
  • Product description(1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+%
  • Packaging100mg
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132740
  • Product description(1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+%
  • Packaging250mg
  • Price$679
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132740
  • Product description(1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+%
  • Packaging1g
  • Price$1741
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberVIT0000765
  • Product description1A,25-DIHYDROXYCHOLECALCIFEROL 95.00%
  • Packaging5MG
  • Price$455.89
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2141
  • Product descriptionCalcitriol
  • Packaging1mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2141
  • Product descriptionCalcitriol
  • Packaging10mM(in 1mL DMSO)
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2141
  • Product descriptionCalcitriol
  • Packaging10mg
  • Price$408
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2141
  • Product descriptionCalcitriol
  • Packaging25mg
  • Price$567
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2141
  • Product descriptionCalcitriol
  • Packaging100mg
  • Price$1986
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2141
  • Product descriptionCalcitriol
  • Packaging500mg
  • Price$4468
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISC1015
  • Product description1,25-Dihydroxyvitamin-D3-[2H3]
  • Packaging1mg
  • Price$2694
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1440 Calcitriol 98% 0.1g $6980 2021-12-16 Buy
Ambeed A132740 (1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+% 2mg $82 2021-12-16 Buy
Ambeed A132740 (1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+% 5mg $188 2021-12-16 Buy
Ambeed A132740 (1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+% 10mg $261 2021-12-16 Buy
Ambeed A132740 (1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+% 50mg $376 2021-12-16 Buy
Ambeed A132740 (1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+% 100mg $452 2021-12-16 Buy
Ambeed A132740 (1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+% 250mg $679 2021-12-16 Buy
Ambeed A132740 (1R,3S,Z)-5-((E)-2-((1R,7AR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 98+% 1g $1741 2021-12-16 Buy
American Custom Chemicals Corporation VIT0000765 1A,25-DIHYDROXYCHOLECALCIFEROL 95.00% 5MG $455.89 2021-12-16 Buy
ApexBio Technology B2141 Calcitriol 1mg $64 2021-12-16 Buy
ApexBio Technology B2141 Calcitriol 10mM(in 1mL DMSO) $350 2021-12-16 Buy
ApexBio Technology B2141 Calcitriol 10mg $408 2021-12-16 Buy
ApexBio Technology B2141 Calcitriol 25mg $567 2021-12-16 Buy
ApexBio Technology B2141 Calcitriol 100mg $1986 2021-12-16 Buy
ApexBio Technology B2141 Calcitriol 500mg $4468 2021-12-16 Buy
Apolloscientific BISC1015 1,25-Dihydroxyvitamin-D3-[2H3] 1mg $2694 2021-12-16 Buy

Properties

Melting point :119-1210C
alpha :D25 +48° (methanol)
Boiling point :474.91°C (rough estimate)
Density :1.0362 (rough estimate)
refractive index :1.4700 (estimate)
Flash point :14 °C
storage temp. :2-8°C
pka :14.43±0.40(Predicted)
form :Solid
color :White to Almost white
λmax :265nm(lit.)
Merck :14,1644
BRN :7559394
BCS Class :2,4
Stability :Air and Light Sensitive
InChIKey :GMRQFYUYWCNGIN-UNVJKIGWSA-N
CAS DataBase Reference :32222-06-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P314 Get medical advice/attention if you feel unwell.

Description

Calcitriol is the active form of vitamin D and is also a kind of hormones in the body. It plays an important role in the regulation of calcium and phosphorus concentration. It can increase the blood calcium level by increasing the intestinal absorption of calcium and can also increase the release of the bone calcium release for increasing the blood calcium levels. This study was first conducted and reported by Michael F. Holick in 1971. The basic principle of action model of calcitriol in many cases is through binding with the vitamin D receptor (the VDR), e.g., the ligand-receptor complex forming between calcitriol and its receptor in the intestinal epithelial cells cytoplasm can be transferred to the nucleus for being as the transcriptional factor in promoting the expression of calcium-binding protein. The increased level of calcium-binding proteins can help the cell to actively transport of more calcium ions, thereby increasing the calcium absorption level. Calcium absorption while maintaining electrical neutrality also requires transporting anions, mainly the absorption of inorganic phosphate ions, so calcitriol also promote the absorption of phosphorus.
Clinically, this drug can be used in the treatment of hypocalcemia, hypoparathyroidism (adult), osteomalacia, rickets (infants), chronic kidney disease, renal osteodystrophy, osteoporosis, as well as the prevention of glucocorticoid induced osteoporosis.
Calcitriol-dimensional molecular structure
Calcitriol-dimensional molecular structure
The above information is edited by the chemicalbook of Dai Xiongfeng.

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