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ChemicalBook >> CAS DataBase List >> Berberine hydrochloride

Berberine hydrochloride

Berberine hydrochloride price.
  • $5 - $650
  • Product name: Berberine hydrochloride
  • CAS: 633-65-8
  • MF: C20H18NO4.Cl
  • MW: 371.81
  • EINECS:211-195-9
  • MDL Number:MFCD00011939
  • Synonyms:TIMTEC-BB SBB006488;NATURAL YELLOW 18 CHLORIDE;NATURAL YELLOW 18;UMBELLATINE;BERBERINE HYDROCHLORIDE;BERBERINE HYDROCHLORIDE N-HYDRATE;LABOTEST-BB LT00440956;CI 75160
46 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Usbiological
Package
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  • 10mM(in 1mL DMSO)
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-B0212-G025
  • Product descriptionBerberine Chloride ≥98%(TLC)
  • Packaging25g
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberC992
  • Product descriptionBerberine Chloride
  • Packaging100g
  • Price$161
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ91754
  • Product descriptionBerberine Chloride
  • Packaging25g
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62311
  • Product descriptionBerberine chloride
  • Packaging5g
  • Price$47
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA256069
  • Product description9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA256069
  • Product description9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+%
  • Packaging5g
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA256069
  • Product description9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+%
  • Packaging10g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA256069
  • Product description9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+%
  • Packaging25g
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA256069
  • Product description9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+%
  • Packaging100g
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA256069
  • Product description9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+%
  • Packaging500g
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1699
  • Product descriptionBerberinehydrochloride
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024671
  • Product descriptionBerberinehydrochloride ≥97%
  • Packaging5g
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024671
  • Product descriptionBerberinehydrochloride ≥97%
  • Packaging10g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99562
  • Product descriptionBerberinehydrochloride ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024671
  • Product descriptionBerberinehydrochloride ≥97%
  • Packaging25g
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024671
  • Product descriptionBerberinehydrochloride ≥97%
  • Packaging100g
  • Price$66
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-B0212-G025 Berberine Chloride ≥98%(TLC) 25g $106 2021-12-16 Buy
AK Scientific C992 Berberine Chloride 100g $161 2021-12-16 Buy
AK Scientific J91754 Berberine Chloride 25g $40 2021-12-16 Buy
Alfa Aesar J62311 Berberine chloride 5g $47 2024-03-01 Buy
Ambeed A256069 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+% 100mg $5 2021-12-16 Buy
Ambeed A256069 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+% 5g $8 2021-12-16 Buy
Ambeed A256069 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+% 10g $15 2021-12-16 Buy
Ambeed A256069 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+% 25g $31 2021-12-16 Buy
Ambeed A256069 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+% 100g $67 2021-12-16 Buy
Ambeed A256069 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride 97+% 500g $235 2021-12-16 Buy
ApexBio Technology N1699 Berberinehydrochloride 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom AS024671 Berberinehydrochloride ≥97% 5g $8 2021-12-16 Buy
Arctom AS024671 Berberinehydrochloride ≥97% 10g $15 2021-12-16 Buy
Arctom CFN99562 Berberinehydrochloride ≥98% 20mg $30 2021-12-16 Buy
Arctom AS024671 Berberinehydrochloride ≥97% 25g $31 2021-12-16 Buy
Arctom AS024671 Berberinehydrochloride ≥97% 100g $66 2021-12-16 Buy

Properties

Melting point :204-206 °C (dec.)
storage temp. :Inert atmosphere,2-8°C
solubility :methanol: soluble
form :Yellow powder
Colour Index :75160
color :Yellow powder
Water Solubility :SOLUBLE IN COLD WATER
BRN :3836585
Stability :Hygroscopic
InChI :InChI=1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
InChIKey :VKJGBAJNNALVAV-UHFFFAOYSA-M
SMILES :C12C=C3C(C(OC)=C(OC)C=C3)=C[N+]=1CCC1=CC3=C(OCO3)C=C21.[Cl-]
CAS DataBase Reference :633-65-8
EPA Substance Registry System :Berberine chloride (633-65-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

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