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ChemicalBook >> CAS DataBase List >> Apremilast

Apremilast

Apremilast price.
  • $50 - $1208.7
  • Product name: Apremilast
  • CAS: 608141-41-9
  • MF: C22H24N2O7S
  • MW: 460.5
  • EINECS:807-237-6
  • MDL Number:MFCD18782607
  • Synonyms:(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;ApreMilast,CC-10004;AcetaMide, N-[2-[(1S)-1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Apremilast (CC-10004;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl);Apremilast (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione;Appleton West;N-[2-[(1S)-1-(3ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide
34 prices
Selected condition:
Brand
  • AccelPharmtech
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Labseeker
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • 2.5g
  • 5G
  • 10g
  • 25G
  • 10mM(in 1mL DMSO)
  • ManufacturerAccelPharmtech
  • Product numberXP2469
  • Product descriptionApremilast 99.00%
  • Packaging5G
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberXP2469
  • Product descriptionApremilast 99.00%
  • Packaging25G
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0437
  • Product descriptionApremilast
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4317
  • Product descriptionApremilast(CC-10004)
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4317
  • Product descriptionApremilast(CC-10004)
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4317
  • Product descriptionApremilast(CC-10004)
  • Packaging10mM(in 1mL DMSO)
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4317
  • Product descriptionApremilast(CC-10004)
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4317
  • Product descriptionApremilast(CC-10004)
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1957
  • Product descriptionApremilast-CC10004 99%
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180924
  • Product descriptionApremilast >98%
  • Packaging100mg
  • Price$414.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180924
  • Product descriptionApremilast >98%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180924
  • Product descriptionApremilast >98%
  • Packaging1000mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA29510
  • Product descriptionApremilast
  • Packaging1g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBA164215
  • Product descriptionApremilast
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBA164215
  • Product descriptionApremilast
  • Packaging50mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA29510
  • Product descriptionApremilast
  • Packaging10g
  • Price$200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech XP2469 Apremilast 99.00% 5G $120 2021-12-16 Buy
AccelPharmtech XP2469 Apremilast 99.00% 25G $260 2021-12-16 Buy
AK Scientific Y0437 Apremilast 10mg $108 2021-12-16 Buy
ApexBio Technology A4317 Apremilast(CC-10004) 5mg $80 2021-12-16 Buy
ApexBio Technology A4317 Apremilast(CC-10004) 10mg $120 2021-12-16 Buy
ApexBio Technology A4317 Apremilast(CC-10004) 10mM(in 1mL DMSO) $180 2021-12-16 Buy
ApexBio Technology A4317 Apremilast(CC-10004) 25mg $200 2021-12-16 Buy
ApexBio Technology A4317 Apremilast(CC-10004) 50mg $250 2021-12-16 Buy
Axon Medchem Axon1957 Apremilast-CC10004 99% 5mg $66 2021-12-16 Buy
Biorbyt Ltd orb180924 Apremilast >98% 100mg $414.8 2021-12-16 Buy
Biorbyt Ltd orb180924 Apremilast >98% 250mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb180924 Apremilast >98% 1000mg $1208.7 2021-12-16 Buy
Biosynth Carbosynth FA29510 Apremilast 1g $50 2021-12-16 Buy
Biosynth Carbosynth BA164215 Apremilast 10mg $97 2021-12-16 Buy
Biosynth Carbosynth BA164215 Apremilast 50mg $162 2021-12-16 Buy
Biosynth Carbosynth FA29510 Apremilast 10g $200 2021-12-16 Buy

Properties

Melting point :152-156°C
Boiling point :741.3±60.0 °C(Predicted)
Density :1.381
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka :14.01±0.20(Predicted)
form :Solid
color :White to Pale Yellow
InChIKey :IMOZEMNVLZVGJZ-QGZVFWFLSA-N
SMILES :C(NC1=CC=CC2=C1C(=O)N([C@@H](C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O)C2=O)(=O)C
CAS DataBase Reference :608141-41-9

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Apremilast (Otezla) was approved by the FDA on March 21, 2014 for the treatment of adult patients with active psoriatic arthritis. Apremilast is a member of a new class of oral small molecule inhibitors of the phosphosphodiesterase 4 (PDE4) enzyme. When PDE4 is inhibited in immune cells, it results in elevation of intracellular cyclic adenosine monophosphate (cAMP) levels, which can regulate inflammatory mediators. The current clinical data indicate that apremilast is an effective and well tolerated option for the management of psoriasis and PsA in adults.

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