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ChemicalBook >> CAS DataBase List >> Aliskiren hemifumarate

Aliskiren hemifumarate

Aliskiren hemifumarate price.
  • $5 - $2656.5
  • Product name: Aliskiren hemifumarate
  • CAS: 173334-58-2
  • MF: C30H53N3O6
  • MW: 551.75832
  • EINECS:630-415-8
  • MDL Number:MFCD10566724
  • Synonyms:(2S,4S,5S,7S)-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-8-methylnonanamide hemifumarate;Aliskiren hemifumarate (2S,4S,5S,7S)-5-Amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamide hemifumarate;ALISKIREN FUMARATE;(2S,4S,5S,7S)-5-Amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamide hemifumarate;Benzeneoctanamide, delta-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-gamma-hydroxy-4-methoxy-3-(3-methoxypropoxy)-alpha,zeta-bis(1-methylethyl)-, (alphas,gammas,deltas,zetas)-, (2E)-2-butenedioate (2:1) (salt);Aliskiren hemifumarate;Unii-C8A0p8G029;Aliskiren-D6 HeMifuMarate
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
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  • Cayman Chemical
  • ChemScene
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Package
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  • 10mM(in 1mL DMSO)
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  • ManufacturerAK Scientific
  • Product numberB702
  • Product descriptionAliskirenhemifumarate
  • Packaging50mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201324
  • Product descriptionAliskirenhemifumarate 98+%
  • Packaging10mg
  • Price$8
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA201324
  • Product descriptionAliskirenhemifumarate 98+%
  • Packaging50mg
  • Price$17
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA201324
  • Product descriptionAliskirenhemifumarate 98+%
  • Packaging100mg
  • Price$25
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA201324
  • Product descriptionAliskirenhemifumarate 98+%
  • Packaging250mg
  • Price$41
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA201324
  • Product descriptionAliskirenhemifumarate 98+%
  • Packaging1g
  • Price$107
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA201324
  • Product descriptionAliskirenhemifumarate 98+%
  • Packaging5g
  • Price$347
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0077967
  • Product descriptionALISKIREN HEMIFUMARATE 95.00%
  • Packaging1MG
  • Price$837.38
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0077967
  • Product descriptionALISKIREN HEMIFUMARATE 95.00%
  • Packaging10MG
  • Price$2656.5
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB2215
  • Product descriptionAliskirenHemifumarate
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB2215
  • Product descriptionAliskirenHemifumarate
  • Packaging100mg
  • Price$188
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB2215
  • Product descriptionAliskirenHemifumarate
  • Packaging1g
  • Price$314
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS474863
  • Product descriptionAliskirenhemifumarate ≥98%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS474863
  • Product descriptionAliskirenhemifumarate ≥98%
  • Packaging50mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS474863
  • Product descriptionAliskirenhemifumarate ≥98%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS474863
  • Product descriptionAliskirenhemifumarate ≥98%
  • Packaging250mg
  • Price$29
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific B702 Aliskirenhemifumarate 50mg $132 2021-12-16 Buy
Ambeed A201324 Aliskirenhemifumarate 98+% 10mg $8 2021-12-16 Buy
Ambeed A201324 Aliskirenhemifumarate 98+% 50mg $17 2021-12-16 Buy
Ambeed A201324 Aliskirenhemifumarate 98+% 100mg $25 2021-12-16 Buy
Ambeed A201324 Aliskirenhemifumarate 98+% 250mg $41 2021-12-16 Buy
Ambeed A201324 Aliskirenhemifumarate 98+% 1g $107 2021-12-16 Buy
Ambeed A201324 Aliskirenhemifumarate 98+% 5g $347 2021-12-16 Buy
American Custom Chemicals Corporation CHM0077967 ALISKIREN HEMIFUMARATE 95.00% 1MG $837.38 2021-12-16 Buy
American Custom Chemicals Corporation CHM0077967 ALISKIREN HEMIFUMARATE 95.00% 10MG $2656.5 2021-12-16 Buy
ApexBio Technology B2215 AliskirenHemifumarate 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology B2215 AliskirenHemifumarate 100mg $188 2021-12-16 Buy
ApexBio Technology B2215 AliskirenHemifumarate 1g $314 2021-12-16 Buy
Arctom AS474863 Aliskirenhemifumarate ≥98% 10mg $5 2021-12-16 Buy
Arctom AS474863 Aliskirenhemifumarate ≥98% 50mg $8 2021-12-16 Buy
Arctom AS474863 Aliskirenhemifumarate ≥98% 100mg $15 2021-12-16 Buy
Arctom AS474863 Aliskirenhemifumarate ≥98% 250mg $29 2021-12-16 Buy

Properties

Melting point :72-75?C
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :White

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Aliskiren is a nonpeptide renin inhibitor (IC50 = 0.6 nM) that selectively binds to the S3 sub-pocket of renin, preventing the conversion of angiotensinogen to angiotensin I, thereby blocking eventual conversion to angiotensin II. Thus, by blocking renin, aliskiren was designed to prevent angiotensin II-mediated arterial vasoconstriction and aldosterone production. Aliskiren is orally bioavailable and, in combination with valsartan , was shown to reduce blood pressure in db/db mice.