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ChemicalBook >> CAS DataBase List >> (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine

(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine

(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine price.
  • $8 - $1647
  • Product name: (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine
  • CAS: 314771-76-1
  • MF: C18H16ClFN4O2
  • MW: 374.8
  • EINECS:1312995-182-4
  • MDL Number:MFCD18642925
  • Synonyms:4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-amine-7-[[(3S)-tetrahydro-3-furanyl]oxy]-;4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-;Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl;N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine;Intermediates of sunitinib;(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine;7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenyl) aMino-6-aMinoquinazoline;Afatinib IMpurity B
15 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Ark Pharm
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • TRC
Package
  • 250MG
  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerAK Scientific
  • Product number3400AB
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
  • Packaging5g
  • Price$231
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3400AB
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
  • Packaging25g
  • Price$721
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number314771761
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
  • Packaging1g
  • Price$242.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number314771761
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
  • Packaging5g
  • Price$727.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0033466
  • Product description(S)-N4-(3-CHLORO-4-FLUOROPHENYL)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLINE-4,6-DIAMINE 95.00%
  • Packaging250MG
  • Price$475.65
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000545777
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98%
  • Packaging250mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000545777
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98%
  • Packaging1g
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000545777
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98%
  • Packaging5g
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000545777
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98%
  • Packaging10g
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000545777
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98%
  • Packaging25g
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM118512
  • Product description6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-[[(S)-tetrahydro-3-furanyl]oxy]quinazoline 95%+
  • Packaging10g
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11146833
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98%
  • Packaging25g
  • Price$417
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number090075
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 95+%
  • Packaging250mg
  • Price$742
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number090075
  • Product description(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 95+%
  • Packaging1g
  • Price$1647
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA355320
  • Product descriptionAfatinib-des(4-dimethylamino-2-en-1-oxo)butyl(Contained~8.5%Ethanol)
  • Packaging10g
  • Price$870
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3400AB (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 5g $231 2021-12-16 Buy
AK Scientific 3400AB (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 25g $721 2021-12-16 Buy
Alichem 314771761 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 1g $242.4 2021-12-16 Buy
Alichem 314771761 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 5g $727.2 2021-12-16 Buy
American Custom Chemicals Corporation CCH0033466 (S)-N4-(3-CHLORO-4-FLUOROPHENYL)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLINE-4,6-DIAMINE 95.00% 250MG $475.65 2021-12-16 Buy
Ark Pharm P000545777 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98% 250mg $8 2021-12-16 Buy
Ark Pharm P000545777 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98% 1g $22 2021-12-16 Buy
Ark Pharm P000545777 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98% 5g $80 2021-12-16 Buy
Ark Pharm P000545777 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98% 10g $159 2021-12-16 Buy
Ark Pharm P000545777 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98% 25g $325 2021-12-16 Buy
Chemenu CM118512 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-[[(S)-tetrahydro-3-furanyl]oxy]quinazoline 95%+ 10g $110 2021-12-16 Buy
Crysdot CD11146833 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 98% 25g $417 2021-12-16 Buy
Matrix Scientific 090075 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 95+% 250mg $742 2021-12-16 Buy
Matrix Scientific 090075 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 95+% 1g $1647 2021-12-16 Buy
TRC A355320 Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl(Contained~8.5%Ethanol) 10g $870 2021-12-16 Buy

Properties

Boiling point :559.0±50.0 °C(Predicted)
Density :1.473±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated, Heated)
pka :5.89±0.30(Predicted)
form :Solid
color :Light Yellow to Light Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.