Pimobendan suppliers
Pimobendan
- CAS:
- 74150-27-9
- MF:
- C19H18N4O2
- MW:
- 334.37
Suppliers by country/region
Company Type
Properties
- Melting point:
- approximate 243℃ (dec.)
- Density
- 1.36
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble5mg/mL, clear (warmed)
- form
- powder
- pka
- 10.55±0.10(Predicted)
- color
- white to beige
- InChI
- InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)
- InChIKey
- GLBJJMFZWDBELO-UHFFFAOYSA-N
- SMILES
- C1(=O)NN=C(C2C=C3NC(C4=CC=C(OC)C=C4)=NC3=CC=2)C(C)C1
- CAS DataBase Reference
- 74150-27-9(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P301+P310+P330
- RIDADR
- UN 2811 6.1 / PGIII
- HS Code
- 2933995300
Use
Pimobendan, a novel cardiotonic vasodilator, was introduced in Japan for the treatment of acute and mild to moderate chronic heart failure. It is a phosphodiesterase Ⅲ inhibitor and is able to enhance sensitization of myocardial contractile regulatory protein to calcium ions. The combination of these effects contribute to its inotropic activity. In patients with severe congestive heart failure, orally administered pimobendan improves cardiac index, stroke volume index, pulmonary wedge pressure, and systemic and pulmonary vascular resistance. Pimobendan is reported to be well tolerated and largely devoid of the proarrhythmic effects of classical phosphodiesterase Ill inhibitors. Studies also suggested that combination of the inotropic agent pimobendan with an ACE inhibitor such as enalapril may be superior to monotherapy for heart failure patients.
231 supplier list of "Pimobendan"
$0.00-0.00 / 1KG
- Product Name:Pimobendan
- Products Intro:Purity: 99%, EP | Package: 1KG;|5KG;|25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Active Pharmaceuticals Ingredients,Peptide,Cosmetics,Nutritional supplements,Fine chemicals
$1.00/ 1kg
- Product Name:Pimobendan
- Products Intro:Purity: 99|Package: 1kg;1.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Fluorouracil,Entecavir,Sofosbuvir,Vinblastine sulfate
$10.00-8.00 / 1kg
- Product Name:Pimobendan
- Products Intro:Purity: 99%|Package: 1kg;10.00;USD|100kg;9.00;USD|1000kg;8.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1-Octadecanol,AMP 95,Polyisobutylene,tetramisole hcl,Ivermectin
$0.00/ 25KG
- Product Name:Pimobendan
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide
$32.00-1.30 / 1kg
- Product Name:Pimobendan
- Products Intro:Purity: 99% | Package: 1kg;32USD|1000kg;1.3USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,pharmaceutical intermediates,Flavors and Fragrances,OLED
$150.00/ 1kg
- Product Name:Pimobendan
- Products Intro:Purity: 99% | Package: 1kg;150USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Candelilla Wax,Cetostearyl alcohol?,Ethyl Oleate,?Sodium Oleate,?Stearyl Alcohol?