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3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one

3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one ??? ???
?? ??:
1262489-36-0
???:
3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one
???(??):
CAY10755;3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one;1H-Phenalen-1-one, 3a,4,5,6,6a,9,9a,9b-octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-
CBNumber:
CB95990374
???:
C21H30O3
??? ??:
330.46
MOL ??:
1262489-36-0.mol

3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one ??

?? ?
475.5±45.0 °C(Predicted)
??
1.111±0.06 g/cm3(Predicted)
?? ??
Store at -20°C
???
Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
??? ??
??
?? ?? (pKa)
13.10±0.70(Predicted)

??

3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one C??? ??, ??, ??

??

CAY10755 is a fungal metabolite that has been found in P. macrospinosa and has anticancer activity. It is cytotoxic to A549, H116, PSN-1, and T98G cancer cells (IC50s = 4.6, 4, 2.2, and 7.7 μM, respectively).

??

3a,?4,?5,?6,?6a,?9,?9a,?9b-?Octahydro-?3a-?hydroxy-?2-?(hydroxymethyl)?-?5,?8,?9a-?trimethyl-?9-?(1-?methyl-?1-?propen-?1-?yl)?-1H-?phenalen-?1-?one is a related compound of phenalenone, which is a class of polyketide natural products.

3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one ?? ?? ? ???

???

?? ??


3a,4,5,6,6a,9,9a,9b-Octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H-phenalen-1-one ?? ??

???( 6)?? ??
??? ?? ??? ?? ?? ? ??
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