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(+)-MK 801 MALEATE

(+)-MK 801 MALEATE ??? ???
?? ??:
77086-19-2
???:
(+)-MK 801 MALEATE
???(??):
()-MK-801;(+)-MK 801 MALEATE;(-)-MK 801 MALEATE;DIZOCILPINE MALEATE;(+)-MK-801 HYDROGEN MALEATE;(-)-MK 801 hydrogen maleate;5,10-Imino-5H-dibenzo[a,d]cycloheptene, 10,11-dihydro-5-methyl-,(5R,10S)-;(5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-iminemaleate;(5R,10S)-(-)-5-METHYL-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5,10-IMINE MALEATE;(5R,10S)-(-)-5-Methyl-10,11-dihydro-(5H)-dibenzo[a.d]cylcoheptene-5,10-iminemaleate
CBNumber:
CB9407482
???:
C16H15N
??? ??:
221.3
MOL ??:
77086-19-2.mol

(+)-MK 801 MALEATE ??

???
68.5-69.5°
??
589 -160.8° (c = 0.032 g/2 ml ethanol)
?? ??
room temp
???
DMSO: >20mg/mL
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optical activity
[α]25/D 117.7°, c = 1 in methanol(lit.)

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WGK ?? 3

(+)-MK 801 MALEATE C??? ??, ??, ??

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Biochemical probe for NMDA receptors.

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(-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801.

???? ??

Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate ((5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate ).

(+)-MK 801 MALEATE ?? ?? ? ???

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(+)-MK 801 MALEATE ?? ??

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