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?????? ??? ???
?? ??:
100-74-3
???:
??????
???(??):
N-??????;??????
???:
N-Ethylmorpholine
???(??):
HEM;Ethylmorpholine;4-ETHYLMORPHOLINE;N-Ethylmorfolin;Texacat NEM;Toyocat -NEM;LUPRAGEN(R) N 104;N-ETHYLMORPHOLINE;4-ethyl-morpholin;4-Ethylmorhpoline
CBNumber:
CB8667476
???:
C6H13NO
??? ??:
115.17
MOL ??:
100-74-3.mol
MSDS ??:
SDS

?????? ??

???
-63 °C (lit.)
?? ?
139 °C (lit.)
??
0.91 g/mL at 20 °C (lit.)
???
8.1 hPa (20 °C)
???
n20/D 1.441(lit.)
???
82 °F
?? ??
Store below +30°C.
???
?? ??
??? ??
??
?? ?? (pKa)
7.67(at 25℃)
??
????? ????, ?? ????
??????(pH)
11.8 (100g/l, H2O, 20℃)
????
1.9%(V)
???
?? ??
???
-63℃
??
Air Sensitive
BRN
102969
?? ??
NIOSH REL: TWA 5 ppm (23 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 20 ppm (94 mg/m3); ACGIH TLV: TWA 5 ppm (adopted).
???
????. ???. ?? ???? ???? ????. ?? ??? ???.
LogP
0.08 at 24.6℃
CAS ??????
100-74-3(CAS DataBase Reference)
NIST
Morpholine, 4-ethyl-(100-74-3)
EPA
N-Ethylmorpholine (100-74-3)
Absorption
cut-off at 300nm
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? C
?? ???? ?? 10-21/22-34
????? 26-36/37/39-45-16
????(UN No.) UN 2920 8/PG 2
OEB A
OEL TWA: 5 ppm (23 mg/m3) [skin]
WGK ?? 1
RTECS ?? QE4025000
F ?????? 8-23
?? ?? ?? 160 °C
TSCA Yes
?? ?? 8
???? II
HS ?? 29349990
?? ?? ??? 100-74-3(Hazardous Substances Data)
?? LD50 orally in Rabbit: 1640 mg/kg LD50 dermal Rabbit 900 mg/kg
IDLA 100 ppm
???? ?? KE-13958
????(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H226 ??? ?? ? ?? ??? ?? ?? 3 ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H311 ??? ???? ??? ?? ?? ?? - ?? ?? 3 ?? GHS hazard pictograms P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
??????:
P210 ?·???·??·????? ????? - ?? ???.
P233 ??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
3
2 0

?????? MSDS


N-Ethylmorpholine

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Colorless, flammable liquid with an ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 400 μg/m3 (85 ppbv) and 1.2 mg/m3 (250 ppbv), respectively (Hellman and Small, 1974).

??

N-Ethylmorpholine is a component of the buffer used in basic peptide separation through anion-exchange chromatography. Further, it acts as a catalyst in the preparation of polyurethane foam.

?? ??

N-Ethylmorpholine is synthesized by the reaction of morpholine with bromoethane.

?? ??

N-Ethylmorpholine appears as a colorless liquid with a strong ammonia-like odor. Severely irritates skin, eyes, and mucous membranes. Moderately soluble in water and less dense than water. Flash point 83°F.

??? ?? ??

Highly flammable. Moderately soluble in water .

?? ???

N-Ethylmorpholine can react vigorously with oxidizing materials. N-Ethylmorpholine dissolves LiAlH4.

???

Irritant to skin and eyes, absorbed by skin. Flammable, moderate fire risk. Toxic by skin absorption.

????

Exposure can cause irritation of eyes, nose and throat. Contact with eyes may result in foggy vision and seeing halos around lights.

Safety Profile

oison by intravenous route. Moderately toxic by ingestion. Mildly toxic by inhalation. A skin and severe eye irritant. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidzing materials. To fight fire, use alcohol foam, foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx.

??? ??

Primary irritant (without allergic reaction). This material is used as a catalyst in polyurethane foam production. It is a solvent for dyes and resins. It is used as an intermediate in surfactant, dye, pharmaceutical, and rubber chemical manufacture

????

Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987).
At an influent concentration of 1,000 mg/L, treatment with GAC resulted in an effluent concentration of 467 mg/L. The adsorbability of the carbon used was 107 mg/g carbon (Guisti et al., 1974).

?? ??

UN2920 Corrosive liquids, flammable, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, 3-Flammable liquid. UN1993 Flammable liquids, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, Technical Name Required

? ???

May form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine,etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Corrodes some metals. Unless inhibited, violent polymerization can occur from heat, sunlight, and contact with strong oxidizers permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Attacks some plastics, rubber and coatings

??? ??

Controlled incineration (oxides of nitrogen are removed from the effluent gas by scrubbers and/or thermal devices).

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