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3,4-Methylenedioxy-beta-nitrostyrene

3,4-Methylenedioxy-beta-nitrostyrene ??? ???
?? ??:
1485-00-3
???:
3,4-Methylenedioxy-beta-nitrostyrene
???(??):
MDBN;MNS (MDBN);NSC 170724;5-(2-Nitrovinyl);AKOS BBS-00006781;Syk Inhibitor III;MNS, 10 mM in DMSO;TIMTEC-BB SBB007833;-nitrostyrene, MDBN);MNS (NSC 170724, MDBN)
CBNumber:
CB8314918
???:
C9H7NO4
??? ??:
193.16
MOL ??:
1485-00-3.mol
MSDS ??:
SDS

3,4-Methylenedioxy-beta-nitrostyrene ??

???
159-163 °C
?? ?
329.36°C (rough estimate)
??
1.4058 (rough estimate)
???
1.5200 (estimate)
?? ??
Sealed in dry,2-8°C
???
DMSO? ?????(?? 50mg/ml).
??? ??
????? ?? ??
??
???
??
Light Sensitive
BRN
192350
???
??? ?? ?????? 2? ?? ??????. DMSO? ???? ?? 1?? ?? -20°?? ??? ? ????.
InChI
InChI=1S/C9H7NO4/c11-10(12)4-3-7-1-2-8-9(5-7)14-6-13-8/h1-5H,6H2
InChIKey
KFLWBZPSJQPRDD-UHFFFAOYSA-N
SMILES
O1C2=CC=C(C=C[N+]([O-])=O)C=C2OC1
CAS ??????
1485-00-3(CAS DataBase Reference)
NIST
3,4-Methylenedioxy-«beta»-nitrostyrene(1485-00-3)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,Xi,T
?? ???? ?? 36/37/38-22-25
????? 36/37/39-26-45
????(UN No.) UN 2811 6.1/PG 3
RTECS ?? WL5270000
HS ?? 29329990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
1
2 0

3,4-Methylenedioxy-beta-nitrostyrene C??? ??, ??, ??

??? ??

yellow powder

??

MDBN is a Src and Syk kinase inhibitor that prevents phosphorylation and cytoskeletal association of GPIIb/IIIa and talin.

???? ??

Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC 50 = 12.7 μ M for thrombin-induced platelet aggregation). Exhibits no effects on Ca 2+ -dependent enzymes, PKC or arachidonic acid metabolism.

3,4-Methylenedioxy-beta-nitrostyrene ?? ?? ? ???

???

?? ??


3,4-Methylenedioxy-beta-nitrostyrene ?? ??

???( 149)?? ??
??? ?? ??? ?? ?? ? ??
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3,4-Methylenedioxy-beta-nitrostyrene ?? ??:

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