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α-(2-???????)?????

α-(2-???????)?????
α-(2-???????)????? ??? ???
?? ??:
1220881-04-8
???:
α-(2-???????)?????
???(??):
α-(2-???????)?????
???:
α-(2-Oxopyrrolidino)valerophenone
???(??):
Oxo-PVP;α-(2-Oxopyrrolidino)valerophenone;1-(1-Benzoylbutyl)-2-pyrrolidinone;2-Pyrrolidinone, 1-(1-benzoylbutyl)-
CBNumber:
CB82545871
???:
C15H19NO2
??? ??:
245.32
MOL ??:
1220881-04-8.mol

α-(2-???????)????? ??

?? ?
422.6±28.0 °C(Predicted)
??
1?+-.0.06 g/cm3(Predicted)
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?? ?? (pKa)
-0.77±0.20(Predicted)
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α-(2-???????)????? C??? ??, ??, ??

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White Solid

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A metabolite of the new designer drug α-Pyrrolidinovalerophenone (PVP) (D291955) in rat. Eleven metabolites of PVP could be identified. The involvement of nine different human cytochrome P 450 (CYP) isoenzymes in the side chain hydroxylation of PVP was investigated and CYP 2B6, 2C19, 2D6, and 3A4 were found to catalyze this reaction.

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