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S-????????

S-????????
S-???????? ??? ???
?? ??:
122130-63-6
???:
S-????????
???(??):
S-????????
???:
S-nitrosocaptopril
???(??):
Captopril Impurity 22;L-Proline, 1-[(2S)-2-methyl-3-(nitrosothio)-1-oxopropyl]-
CBNumber:
CB81310384
???:
C9H14N2O4S
??? ??:
246.28
MOL ??:
122130-63-6.mol

S-???????? ??

?? ?
470.9±55.0 °C(Predicted)
??
1.47±0.1 g/cm3(Predicted)
?? ??
Hygroscopic, Refrigerator, Under inert atmosphere
???
DMSO(?? ???), ?(?? ???), ???
??? ??
?? ??.
?? ?? (pKa)
3.52±0.20(Predicted)
??
???
???
???

??

?? TDLo orl-rat: 2000 mg/kg FCTOD7 39,1135,2001

S-???????? C??? ??, ??, ??

??

S-Nitrosocaptopril is an ACE inhibitor and NO donor.

???

Moderately toxic by ingestion.

Safety Profile

Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic vapors of NOx and SOx

S-???????? ?? ?? ? ???

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S-???????? ?? ??

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