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Zavegepant

Zavegepant ??? ???
?? ??:
1337918-83-8
???:
Zavegepant
???(??):
BHV-3500;Vazegepant;Zavegepant;Zevagepant;BMS 742413);Vazegepant free base;Zavegepant (Vazegepant;Zavegepant (BHV-3500, BMS-742413);(R)-N-(3-(7-Methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)piperazin-1-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide;N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide
CBNumber:
CB75551430
???:
C36H46N8O3
??? ??:
638.8
MOL ??:
1337918-83-8.mol

Zavegepant ??

?? ?
933.7±65.0 °C(Predicted)
??
1.285±0.06 g/cm3(Predicted)
?? ?? (pKa)
11.68±0.70(Predicted)
??? ??
Solid
??
White to off-white

??

Zavegepant C??? ??, ??, ??

??

Zavegepant, also known as Vazegepant, BHV-3500 and BMS 742413, is a highly potent, selective and structurally unique small molecule CGRP receptor antagonist. Vazegepant is the first and only CGRP receptor antagonist for intranasal administration currently in development for the acute treatment of migraine.

Zavegepant ?? ?? ? ???

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Zavegepant ?? ??

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