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5-CARBOXYCYTOSINE

5-CARBOXYCYTOSINE ??? ???
?? ??:
3650-93-9
???:
5-CARBOXYCYTOSINE
???(??):
5-CARBOXYCYTOSINE;Uracil Impurity 8;Imidacloprid Impurity 30;cytosine-5-carboxylic acid;4-AMINO-5-CARBOXY-2-HYDROXYPYRIMIDINE;5-CARBOXYCYTOSINE ISO 9001：2015 REACH;4-AMINO-5-CARBOXY-2-HYDROXYPYRIMIDINE 97%;4-Amino-2-hydroxy-5-pyrimidinecarboxylicacid;6-amino-2-oxo-1H-pyrimidine-5-carboxylic acid;4-Amino-2-hydroxypyrimidine-5-carboxylic acid
CBNumber:
CB7390159
???:
C5H5N3O3
??? ??:
155.11
MOL ??:
3650-93-9.mol

5-CARBOXYCYTOSINE ??

???
256-257 °C
??
1.88±0.1 g/cm3(Predicted)
?? ??
Refrigerator, under inert atmosphere
???
???? ??? ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
-3.50±0.20(Predicted)
??
?? ????? ?? ?????
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
?? ?? IRRITANT
???? ?? KE-09369
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

5-CARBOXYCYTOSINE C??? ??, ??, ??

??

Cytosine derivatives, such as 5-Carboxylcytosine, are involved with a wide variety of biological functions including cytosine methylation, gene expression, genome stability, and chromatin modification. In addition, 5-Carboxylcytosine interacts with the RNA polymerase II elongation complex that can influence the pluripotent states during early embryonic development.

??

ChEBI: A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a carboxy group.

5-CARBOXYCYTOSINE ?? ?? ? ???

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??? ????? ?? ????(???) ?? 2-????-3-????????? ????

?? ??

5-CARBOXYCYTOSINE ?? ??

???( 40)?? ??
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5-CARBOXYCYTOSINE ?? ??:

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