Anti-Zimp7;Anti-Net27;Anti-ZMIZ2;Anti-Hzimp7;Anti-Kiaa1886;Anti-Dkfzp761i2123;Anti-PIAS-like protein Zimp7;Anti-ZMIZ2 antibody produced in rabbit;Anti-Zinc finger, miz-type containing 2;Anti-PIASz (N-term) antibody produced in rabbit
PIASz is a members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family of proteins, negative regulators of the Janus family of tyrosine kinase (JAK)-signal transducer and activator of transcription pathway. PIAS proteins have been shown to act as transcriptional co-regulators of multiple signaling pathways in various cellular processes. PIASz increases ligand-dependent transcriptional activity of androgen receptor and other nuclear hormone receptors, possibly through alteration of chromatin structure by SWI/SNF-like BAF complexes.