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????????-PC

????????-PC
????????-PC ??? ???
?? ??:
146797-82-2
???:
????????-PC
???(??):
????????-PC
???:
ARACHIDONOYL THIO-PC
???(??):
Thiopc;ARACHIDONOYL THIO-PC;YDSCLGYBUIDZNF-WWBBCYQPSA-N;2-DEOXY-2-THIO ARACHIDONOYL PC;Arachidonoyl thio-PC (substrate);2-DEOXY-2-THIOARACHIDONOYLPHOSPHATIDYLCHOLINE;1-hexadecyl-2-arachidonoylthio-2-deoxyglycero-3-phosphorylcholine;1-Hexadecyl-2-arachidonoylthio-2-deoxy-sn-glycero-3-phosphorylcholine;1-O-HEXADECYL-2-DEOXY-2-THIO-R-(5Z,8Z,11Z,14Z-EICOSATETRAENOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE;Ethanaminium, 2-[[[(2R)-3-(hexadecyloxy)-2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]thio]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
CBNumber:
CB6762395
???:
C44H82NO6PS
??? ??:
784.16
MOL ??:
146797-82-2.mol

????????-PC ??

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Store at -20°C
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DMF: 25 mg/ml; DMSO: 25 mg/ml; Water: 0.5 mg/ml
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Liquid
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Colorless to light yellow

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Arachidonoyl thio-PC is a substrate for many phospholipase A2s (PLA2s) including sPLA2, cPLA2, and iPLA2. Cleavage of the sn-2 fatty acid by PLA2 results in generation of a free thiol which reacts with chromogenic reagents such as DTNB (Ellman’s reagent) and DTP to allow quantitation of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by excluding or inhibiting sPLA2 and iPLA2 activities in the assay.

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