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4-Chloro-2-fluorophenylacetonitrile

4-Chloro-2-fluorophenylacetonitrile ??? ???
?? ??:
75279-53-7
???:
4-Chloro-2-fluorophenylacetonitrile
???(??):
4-Chloro-2-fluorobenzylcyanide;2-FLUORO-4-CHLOROBENZYL CYANIDE;4-CHLORO-2-FLUOROPHENYLACETONITRILE;4-Chloro-2-fluorobenzeneacetonitrile;2-(4-Cloro-2-fluorophenyl)acetonitrile;Benzeneacetonitrile, 4-chloro-2-fluoro-;2-(4-CHLORO-2-FLUOROPHENYL)ACETONITRILE;4-Chloro-2-fluorophenylacetonitrile, 98+%;4-CHLORO-2-FLUOROPHENYLACETONITRILE: TECH.;2-(4-Chloro-2-fluorophenyl)acetonitrile, tech
CBNumber:
CB6327286
???:
C8H5ClFN
??? ??:
169.58
MOL ??:
75279-53-7.mol

4-Chloro-2-fluorophenylacetonitrile ??

???
37-41℃
?? ?
133 °C
??
1.286±0.06 g/cm3(Predicted)
?? ??
2-8°C
??? ??
??? ??
??
???
LogP
2.34 at 25℃ and pH7
CAS ??????
75279-53-7(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T,C,Xn
?? ???? ?? 20/21/22-36/37/38
????? 26-36/37/39
????(UN No.) 3276
?? ?? ?? Toxic
?? ?? 6.1
HS ?? 2926907090
????(GHS): GHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H311 ??? ???? ??? ?? ?? ?? - ?? ?? 3 ?? GHS hazard pictograms P280, P302+P352, P312, P322, P361,P363, P405, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 ???? ??? ?? ?? ?? ?? ?? 4 ?? GHS hazard pictograms P261, P271, P304+P340, P312
??????:
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P309 ?????? ?? ?? ?? ??
P310 ?? ????(??)? ??? ????. ???? ?? ????(??)? ??? ????.
NFPA 704
1
2 0

4-Chloro-2-fluorophenylacetonitrile C??? ??, ??, ??

??

4-Chloro-2-fluorobenzeneacetonitrile is an intermediate used to prepare RG7388, a potent and selective p53-MDM2 inhibitor.

4-Chloro-2-fluorophenylacetonitrile ?? ?? ? ???

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4-Chloro-2-fluorophenylacetonitrile ?? ??

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4-Chloro-2-fluorophenylacetonitrile ?? ??:

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