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????? ??? ???
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28981-97-7
???:
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???(??):
?????
???:
Alprazolam
???(??):
Xanax;Zolam;Trankimazin;8-Chloro-1-methyl-6-phenyl-4H-2,3,5,10b-tetraazabenzo[e]azulene;8-CHLORO-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPINE;d65mt;Tafil;TUS-1;Xanor;C06817
CBNumber:
CB6141398
???:
C17H13ClN4
??? ??:
308.76
MOL ??:
28981-97-7.mol
MSDS ??:
SDS

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???
228-228.50C
?? ?
463.51°C (rough estimate)
??
1.2000 (rough estimate)
???
1.6110 (estimate)
???
11 °C
?? ??
2-8°C
???
H2O: ???
?? ?? (pKa)
2.37±0.40(Predicted)
???
70mg/L(????)
BCS Class
1
CAS ??????
28981-97-7(CAS DataBase Reference)
NIST
Alprazolam(28981-97-7)
EPA
Alprazolam (28981-97-7)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,T,F
?? ???? ?? 22-39/23/24/25-23/24/25-11
????? 36-45-36/37-16-7
????(UN No.) 3249
WGK ?? 3
RTECS ?? XZ5473000
?? ?? 6.1(b)
???? III
HS ?? 2933910000
?? ?? ??? 28981-97-7(Hazardous Substances Data)
?? LD50 in mice, rats (mg/kg): 1020, >2000 orally; 540, 610 i.p. (Nakajima)
DEA Controlled Substances CSCN: 2882
CAS SCH: Ⅳ
NARC: N
???? ?? KE-05770
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P330 ?? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
3
0 0

????? MSDS


Alprazolam

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Alprazolam (Item No. 14255) is an analytical reference material categorized as a benzodiazepine. Alprazolam is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

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White Crystalline Solid

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Controlled substance (depressant). Anxiolytic

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ChEBI: A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individu ls that have taken this drug.

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Alprazolam, 8-chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine (Xanax), israpidly absorbed from the GI tract. Protein binding is lower(~70%) than with most benzodiazepines because of itslower lipophilicity.α-Hydroxylation of the methyl group tothe methyl alcohol (a reaction analogous to benzylic hydroxylation)followed by conjugation is rapid; consequently,the duration of action is short. The drug is a highlypotent anxiolytic on a milligram basis.

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