CATAPOL;CATALPOL;Catalpol-RM;catalpinoside;Catapol ,>=98%;Catalpol,Catalnol;CATALPOL WITH HPLC;Catalpol 2415-24-9;,6-beta,6a-alpha))-;Digitalis purpurea L
Catalpol is an iridoid glycoside that has been isolated from R. glutinosa and has diverse biological activities, including anti-apoptotic, pro-angiogenic, and radioprotective properties. It protects against mitochondrial pathway-dependent apoptosis in PC12 rat adrenal pheochromocytoma cells and H9c2 rat embryonic ventricular myocardial cells when used at a concentration of 10 μM. Catalpol pretreatment reduces apoptosis and improves viability in AHH-1 human lymphocyte cells exposed to ionizing radiation and reduces intestinal damage induced by radiation in mice when used at concentrations and doses ranging from of 25 to 100 μg/ml and 25 to 100 mg/kg, respectively. In a rat model of stroke, catalpol (5 mg/kg, i.p.) increases the expression of erythropoietin and VEGF and improves angiogenesis in the brain.
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Light brown powder
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Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.