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5-???-2-??-3-??????

5-???-2-??-3-??????
5-???-2-??-3-?????? ??? ???
?? ??:
2882-15-7
???:
5-???-2-??-3-??????
???(??):
5-???-2-??-3-??????
???:
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
???(??):
NSC 97026;5-MeO,2-Me-IAA;VITAS-BB TBB000392;TIMTEC-BB SBB003362;Indomethacin USP RC A;Acemetacin Impurity 3;Indomethacin Impurity 13;Indometacin EP Impurity B;Indomethacin EP Impurity B;De(chlorobenzoyl)indomethacin.
CBNumber:
CB5488768
???:
C12H13NO3
??? ??:
219.24
MOL ??:
2882-15-7.mol
MSDS ??:
SDS

5-???-2-??-3-?????? ??

???
161-163 °C (lit.)
?? ?
360.05°C (rough estimate)
??
1.1825 (rough estimate)
???
1.5270 (estimate)
?? ??
2-8°C
???
??? ? ???
??? ??
??? ??
?? ?? (pKa)
4.22±0.30(Predicted)
??
??~?? ??? ?? ?? ????
CAS ??????
2882-15-7(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????? 24/25
WGK ?? 3
HS ?? 29349990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
1 0

5-???-2-??-3-?????? C??? ??, ??, ??

??? ??

slightly yellow fine crystalline powder

??

5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection.

?? ??

5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin.

5-???-2-??-3-?????? ?? ?? ? ???

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5-???-2-??-3-?????? ?? ??

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