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PhiKan 083 hydrochloride

PhiKan 083 hydrochloride ??? ???
?? ??:
1050480-30-2
???:
PhiKan 083 hydrochloride
???(??):
PhiKan 083 HCl;PhiKan083 hydrochloride >=98% (HPLC);1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine hydrochloride
CBNumber:
CB43411342
???:
C16H19ClN2
??? ??:
274.79
MOL ??:
1050480-30-2.mol
MSDS ??:
SDS

PhiKan 083 hydrochloride ??

?? ??
Store at -20°C
???
Soluble to 50 mM in water and to 100 mM in DMSO
??? ??
Solid
??
White to off-white
???
Water: 2 mg/mL (7.28 mM and warming)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

PhiKan 083 hydrochloride C??? ??, ??, ??

??

PhiKan-083 is a p53 stabilizing agent. PhiKan-083 preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan-083 slows rate of thermal denaturation of p53-Y220C.

PhiKan 083 hydrochloride ?? ?? ? ???

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PhiKan 083 hydrochloride ?? ??

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