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Budralazine

Budralazine ??? ???
?? ??:
36798-79-5
???:
Budralazine
???(??):
PTLZ;DJ-1461;Butrazine;Buterazine;BUDRALAZINE;1,2H-PHTHALAZONE;DIHYDROOXOPHTHALAZINE;Budralazine USP/EP/BP;1,2-DIHYDROPHTHALAZIN-1-ONE;1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
CBNumber:
CB4282099
???:
C14H16N4
??? ??:
240.3
MOL ??:
36798-79-5.mol

Budralazine ??

???
183-185 °C(lit.)
?? ?
373.02°C (rough estimate)
??
1.1506 (rough estimate)
???
1.6000 (estimate)
?? ??
Amber Vial, -20°C Freezer, Under inert atmosphere
???
?????(?? ???), DMSO(?? ???), ???(?? ???, ??)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
9.54±0.70(Predicted)
??
?? ????? ?????
???
???
CAS ??????
36798-79-5(CAS DataBase Reference)

??

??? ?? Xn
?? ???? ?? 22
????? 22-24/25
WGK ?? 3
RTECS ?? TH9185000
?? LD50 in mice, rats (mg/kg): 1820, 620 orally; 4020, 3570 i.p. (Onodera)

Budralazine C??? ??, ??, ??

??

Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.

??

Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.

Budralazine ?? ?? ? ???

???

?? ??


Budralazine ?? ??

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