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N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide

N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide ??? ???
?? ??:
726169-73-9
???:
N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide
???(??):
Mocetinostat;MGCD0103;MG0103;CS-1929;Mocetinostat, >=98%;CD0103) Mocetinostat;MGCD0103(Mocetinostat);Mocetinostat (MGCD0103);Mocetinostat (MGCD0103,MG0103);MGCD0103; MGCD 0103; MGCD-0103
CBNumber:
CB42484945
???:
C23H20N6O
??? ??:
396.44
MOL ??:
726169-73-9.mol
MSDS ??:
SDS

N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide ??

???
>170oC (dec.)
??
1.340±0.06 g/cm3(Predicted)
?? ??
RT
???
DMSO? ???(?? 25mg/ml)
?? ?? (pKa)
13.13±0.70(Predicted)
??? ??
??
??? ??
??? ??
??
???
???
??? ?? ?????? 1? ?? ??????. DMSO? ???? -20°C?? ?? 2?? ?? ??? ? ????.

??

N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide C??? ??, ??, ??

??

Mocetinostat is a multi-targeted histone deacetylase inhibitor used in cancer therapy. Mocetinostat is undergoing clinical trials for the treatment of various cancers including follicular lymphoma, Hodgkin’s lymphoma and acute myelogenous leukemia.

N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide ?? ?? ? ???

???

??4-((4-(???-3-?)????-2-????)??)????? ??4-(???????)????? 4-({[4-(???-3-?)????-2-?]???}??)??? 3-?????? O-???????

?? ??

N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide ?? ??

???( 154)?? ??
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N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide ?? ??:

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