????????
|
|
???????? ??
- ???
- 200-2020C
- ?? ??
- 2-8°C
- ???
- DMSO? ???? ?????.
- ??? ??
- Solid
- ??
- ???? ?? ???
- ??
- Hygroscopic
- ???
- ???
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38-20/21/22 | ||
| ????? | 26-36/37/39-36 | ||
| ????(UN No.) | UN2811 | ||
| WGK ?? | 3 | ||
| RTECS ?? | TL9800000 | ||
| ?? ?? | 6.1 | ||
| ???? | III | ||
| HS ?? | 2934302300 | ||
| ?? | guinea pig,LD50,intraperitoneal,299mg/kg (299mg/kg),Pharmazie. Vol. 38, Pg. 749, 1983. |
???????? C??? ??, ??, ??
??? ??
Off-White Solid??
Antipsychotic?? ??
The member ofthe piperazine subgroup with a trifluoromethyl group at the2-position of the phenothiazine system and the most potentantipsychotic phenothiazine on a milligram basis is fluphenazinehydrochloride, 4-[3-[2-(trifluoromethyl)phenazin-10-yl] propyl]-1-piperazineethanol dihydrochloride, 10[3-[4-(2-hydroxyethyl)piperazinyl]propyl]-2-trifluoromethylphenothiazine dihydrochloride (Permitil, Prolixin). It is alsoavailable as two lipid-soluble esters for depot intramuscularinjection, the enanthate (heptanoic acid ester) and the decanoateester. These long-acting preparations have use intreating psychotic patients who do not take their medicationor are subject to frequent relapse.???????? ?? ?? ? ???
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|---|---|---|---|---|---|
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???????? ?? ??:
???? ?????????? ????? 2-???-4-(????????)????? ????????? ???????? ?????????? ??????????? 1-(2-???????)????
Promazine hydrochloride
Promazine
1,3-DIAMINOPROPANE DIHYDROCHLORIDE
1-(3-AMINOPROPYL)-4-METHYLPIPERAZINE
1-(2-Hydroxyethyl)-4-methylpiperazine
10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine
1-(3-AMINOPROPYL)PIPERAZINE
1,3-Propanediamine,N3,N3-diethyl-1-phenyl-
10-METHYLPHENOTHIAZINE
4-TRIFLUOROMETHYL DIPHENYL SULFIDE
2-(Trifluoromethyl)phenothiazine
1-[3-(DIMETHYLAMINO)PROPYL]PIPERAZINE