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11-[3-(??????)???]-6,11-????????[b,e]???-11-?

11-[3-(??????)???]-6,11-????????[b,e]???-11-?
11-[3-(??????)???]-6,11-????????[b,e]???-11-? ??? ???
?? ??:
4504-88-5
???:
11-[3-(??????)???]-6,11-????????[b,e]???-11-?
???(??):
11-[3-(??????)???]-6,11-????????[b,e]???-11-?
???:
11-[3-(dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol
???(??):
Doxepinol;Doxepin EP Impurity B;Doxepin USP Related Compound B;Doxepin Hydrochloride impurity B;(11RS)-11-[3-(Dimethylamino)-propyl;Doxepin Hydrochloride EP Impurity B;Doxepin Impurity 2(Doxepin EP Impurity B);Doxepin Related Compound B USPRS /EP IMP B;Doxepin EP Impurity B (Doxepinol)(USP RC B);11-[3-(dimethylamino)propyl]-6H-benzo[c][1]benzoxepin-11-ol
CBNumber:
CB3901317
???:
C19H23NO2
??? ??:
297.39
MOL ??:
4504-88-5.mol
MSDS ??:
SDS

11-[3-(??????)???]-6,11-????????[b,e]???-11-? ??

???
114 - 118°C
?? ?
439.2±45.0 °C(Predicted)
??
1.123±0.06 g/cm3(Predicted)
?? ??
Refrigerator, under inert atmosphere
???
??????(?? ???), ?????(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
13.58±0.20(Predicted)
??
???? ?? ???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 2932996560
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P330 ?? ?????.
P501 ...? ??? / ??? ?? ???.

11-[3-(??????)???]-6,11-????????[b,e]???-11-? C??? ??, ??, ??

??

11-[3-(Dimethylamino)propyl]-6,11-dihydrocibenz[b,e]oxepin-11-ol is an impurity in the synthesis of Doxepin (D550000), used clinically to treat anxiety and depression. Doxepin is an antidepressant.

11-[3-(??????)???]-6,11-????????[b,e]???-11-? ?? ?? ? ???

???

?? ??


11-[3-(??????)???]-6,11-????????[b,e]???-11-? ?? ??

???( 65)?? ??
??? ?? ??? ?? ?? ? ??
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11-[3-(??????)???]-6,11-????????[b,e]???-11-? ?? ??:

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