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5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE

5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE ??? ???
?? ??:
158942-04-2
???:
5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE
???(??):
SB 206553;SB 206553 HCL;SB 206553 HYDROCHLORIDE;SB-206553 hydrochloride hydrate;SB-206553 hydrate hydrochloride;1-amino-2-bromo-4-(2-methylanilino)anthracene-9,10-dione;5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE;5-Methyl-N-(pyridin-3-yl)-2,3-dihydropyrrolo[2,3-f]indole-1(5H)-carboxamide;5-METHYL-3,5-DIHYDRO-2H-PYRROLO[2,3-F]INDOLE-1-CARBOXYLIC ACID PYRIDIN-3-YLAMIDE;Benzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide, 3,5-dihydro-5-methyl-N-3-pyridinyl-
CBNumber:
CB3726158
???:
C17H16N4O
??? ??:
292.34
MOL ??:
158942-04-2.mol

5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE ??

?? ?
575.4±50.0 °C(Predicted)
??
1.33±0.1 g/cm3(Predicted)
?? ??
Desiccate at RT
???
H2O: 30 mg/mL
?? ?? (pKa)
13.50±0.20(Predicted)
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WGK ?? 3

5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE C??? ??, ??, ??

???? ??

Potent and selective 5-HT 2B /5-HT 2C receptor antagonist (rat 5-HT 2B pA 2 = 8.89, human 5-HT 2C pK i = 7.92). Displays > 80-fold selectivity over all other 5-HT receptor subtypes and a variety of other receptors (pK i < 6). Centrally active following oral administration in vivo .

5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE ?? ?? ? ???

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5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE ?? ??

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