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PD 123319 ditrifluoroacetate

PD 123319 ditrifluoroacetate ??? ???
?? ??:
130663-39-7
???:
PD 123319 ditrifluoroacetate
???(??):
CS-953;PD 123,319;PD123319 TFA;PD123319, >=98%;(S)-(+)-PD 123319;ditrifluoroacetate;PD-123319 TFA salt;PD-123319 free base;PD 123319 ditrifluor;PD 123319, 10 mM in DMSO
CBNumber:
CB3669147
???:
C31H32N4O3
??? ??:
508.61
MOL ??:
130663-39-7.mol

PD 123319 ditrifluoroacetate ??

?? ?
775.8±60.0 °C(Predicted)
??
1.22±0.1 g/cm3(Predicted)
?? ??
2-8°C
???
H2O: 12 mg/mL
??? ??
??
?? ?? (pKa)
2.80±0.20(Predicted)
???
?? 100mM?? ???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26
WGK ?? 3
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

PD 123319 ditrifluoroacetate C??? ??, ??, ??

??

PD 123319 is a selective non-peptide angiotensin AT2 receptor antagonist.

??

ChEBI: An imidazopyridine consisting of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine having 4-(dimethylamino)-3-methylbenzyl, diphenylacetyl and carboxy and groups at positions 1, 5 and 6 respectively

???? ??

Potent, selective, non-peptide angiotensin AT 2 receptor antagonist. IC 50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.

PD 123319 ditrifluoroacetate ?? ?? ? ???

???

?? ??

PD 123319 ditrifluoroacetate ?? ??

???( 120)?? ??
??? ?? ??? ?? ?? ? ??
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PD 123319 ditrifluoroacetate ?? ??:

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