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Tridihexethyl Chloride, is an anticholinergic, antimuscarinic and antispasmodic drug.

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Tridihexethyl chloride,3-cyclohexyl-3-hydroxy-3-phenylpropyl)triethylammoniumchloride (Pathilon), is a white, bitter, crystalline powderwith a characteristic odor. The compound is freely soluble inwater and alcohol, with aqueous solutions being nearly neutralin reaction.
Although this drug, introduced in 1958, has ganglionblockingactivity, its peripheral atropine-like activity predominates;therefore, its therapeutic application has beenbased on the latter activity. It possesses the antispasmodicand the antisecretory activities characteristic of this group,but because of its quaternary character, it is valueless in relievingParkinson syndrome.

Clinical Use

tridihexethyl chloride is useful for adjunctive therapy in a wide varietyof GI diseases, such as peptic ulcer, gastric hyperacidity,and hypermotility and spastic conditions, such as spasticcolon, functional diarrhea, pylorospasm, and other relatedconditions. Because its action is predominantly antisecretory,it is more effective in gastric hypersecretion than in hypermotilityand spasm. It is best administered intravenouslyfor the latter conditions.
The side effects usually found with effective anticholinergictherapy occur with the use of this drug. These are drynessof mouth, mydriasis, and such. As with other anticholinergics,care should be exercised when administering the drug topatients with glaucomatous conditions, cardiac decompensation,and coronary insufficiency. It is contraindicated inpatients with obstruction at the bladder neck, prostatic hypertrophy,stenosing gastric and duodenal ulcers, or pyloric orduodenal obstruction.

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TargetMol Chemicals Inc.		support@targetmol.com	United States	38664	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	19902	58
J & K SCIENTIFIC LTD.	18210857532	jkinfo@jkchemical.com	China	96815	76
Sinopharm Chemical Reagent Co,Ltd.	86-21-63210123	sj_scrc@sinopharm.com	China	9815	79
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57422	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18478	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24886	58
LGC Science (Shanghai) Ltd.	17717235263	cindy.yang@lgcgroup.com	China	17730	58
	4008-099-669	23419001name@qq.com	CHINA	73043	58
Santa Cruz Biotechnology Inc	60936350	scbt@scbt.com	China	222068	58

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