ChemicalBook >?? ???? >MI-192
MI-192
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MI-192 ??
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- 565.0±50.0 °C(Predicted)
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- 1.30±0.1 g/cm3(Predicted)
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- 2-8°C
- ???
- ≤5mg/ml in DMSO;1mg/ml in dimethyl formamide
- ?? ?? (pKa)
- 13.08±0.70(Predicted)
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MI-192 C??? ??, ??, ??
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MI-192 is a histone deacetylase (HDAC) 2 and 3 inhibitor. It also showed cytotoxic effect by inducing differentiation and apoptosis in acute myeloid leukemia cells in human.Biochem/physiol Actions
MI192 is a potent and selective histone deacetylase 3 (HDAc 3) inhibitor that inhibits IL-6 production in peripheral blood mononuclear cells (PBMCs) from rheumatoid arthritis (RA) but not healthy PBMCs.MI-192 ?? ?? ? ???
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MI-192 ?? ??
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