ChemicalBook >?? ???? >?????-PEG-5-t-??????
?????-PEG-5-t-??????
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?????-PEG-5-t-?????? ??
- ?? ?
- 406.8±35.0 °C(Predicted)
- ??
- 1.04746 g/mL
- ???
- n/D 1.4492
- ?? ??
- 2-8°C
- ???
- Soluble in Water, DCM
- ??? ??
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- ?? ?? (pKa)
- 14.36±0.10(Predicted)
- ??
- Colorless to Light yellow to Light orange
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| HS ?? | 2918999090 |
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?????-PEG-5-t-?????? C??? ??, ??, ??
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This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.?????-PEG-5-t-?????? ?? ?? ? ???
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?????-PEG-5-t-?????? ?? ??
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?????-PEG-5-t-?????? ?? ??:
Hydroxy-PEG4-CH2CO2Me
Bis-PEG6-t-butyl ester
tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate
3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
PEG4-acid
HO-PEG6-CH2CH2COOH
α,ω-dipropionic acid tetraethylene glycol
Bis-PEG6-acid
alpha-[3-(1,1-Dimethylethoxy)-3-oxopropyl]-omega-hydroxypoly(oxy-1,2-ethanediyl)
HO-PEG8-CH2CH2COOH
Hydroxy-PEG5-acid
PEG5-acid
PEG7-t-butly ester
PEG9-t-butly ester
HO-PEG10-tBu
Hydroxy-PEG3-t-butylester
Hydroxy-PEG9-t-butyl ester
TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-