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Phe-Lys(FMoc)-PAB

Phe-Lys(FMoc)-PAB ??? ???
?? ??:
2149584-03-0
???:
Phe-Lys(FMoc)-PAB
???(??):
Phe-Lys(FMoc)-PAB
CBNumber:
CB32730942
???:
C37H40N4O5
??? ??:
620.75
MOL ??:
2149584-03-0.mol

Phe-Lys(FMoc)-PAB ??

?? ?
931.0±65.0 °C(Predicted)
??
1.260±0.06 g/cm3(Predicted)
?? ?? (pKa)
12.24±0.46(Predicted)
??? ??
Solid
??
Off-white to light yellow
InChIKey
RCPHMUPZDFKBDS-WPFLMDKRNA-N
SMILES
C(C1C2=CC=CC=C2C2=CC=CC=C12)OC(=O)NCCCC[C@H](NC(=O)[C@@H](N)CC1C=CC=CC=1)C(=O)NC1C=CC(CO)=CC=1 |&1:22,26,r|
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

Phe-Lys(FMoc)-PAB C??? ??, ??, ??

??

Phe-Lys(FMoc)-PAB is a protease-cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

Phe-Lys(FMoc)-PAB ?? ?? ? ???

???

?? ??

Phe-Lys(FMoc)-PAB ?? ??

???( 23)?? ??
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