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403982-64-9
???:
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???(??):
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SPERMINE DIHYDRATE
???(??):
GEROTINE;NEURIDINE;GERONTINE;MUSCULAMINE;SPERMINE DIHYDRATE;SPERMINE FREE BASE;GERONTINE DIHYDRATE;DIAMINOPROPYLTETRAMETHYLENEDIAMINE;N,N'-BIS(3-AMINOPROPYL)-1,4-DIAMINOBUTANE;N,N'-BIS AMINOPROPYL-1,4-BUTYLENE DIAMINE
CBNumber:
CB3217243
???:
C10H30N4O2
??? ??:
238.37
MOL ??:
403982-64-9.mol
MSDS ??:
SDS

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???
63-64 °C
?? ?
150 °C5 mm Hg(lit.)
???
>230 °F
?? ??
2-8°C
???
H2O: 50 mg/mL
??? ??
??? ???
??????(pH)
12.0-13.5 (25℃, 1M in H2O)
???
H2O: 1M at20°C, clear, colorless
?? ??(λmax)
λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.20
??
Air Sensitive & Hygroscopic
BRN
7526933
CAS ??????
403982-64-9(CAS DataBase Reference)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? C
?? ???? ?? 34
????? 26-36/37/39-45
????(UN No.) UN 3259 8/PG 2
WGK ?? 3
RTECS ?? EJ7175000
F ?????? 3-10-34
TSCA Yes
?? ?? 8
HS ?? 2921290090
????(GHS): GHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
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P260 ??·?·??·???·??·...·????? ???? ???.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P363 ?? ??? ??? ??? ?????.

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Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

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