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- ???
- <25 °C
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- bp0.6 127-128°
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- 1.06±0.1 g/cm3(Predicted)
- ?? ?? (pKa)
- 3.14±0.10(Predicted)
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Originator
Bled, Poli, Italy ,1978Manufacturing Process
To a solution of 142 g (1 mol) of trans-3,3,5-trimethylcyclohexanol in 400 cc of anhydrous benzene heated to 70 C is added gradually 178 g (1 mol) of niacin chloride hydrochloride. Heating is carried out under reflux conditions for 3 hours, the solution is cooled, the ester hydrochloride is filtered off and then recrystallized in an ethanol-ethyl ether mixture to obtain 227 g (80% yield) of product melting at 155°C to 157°C.By treating the hydrochloride with an aqueous solution of NaOH at 0°C, the free base is obtained in the form of a viscous white liquid which boils at 115°C under 0.05 mm.
Therapeutic Function
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| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38630 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 |
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