ChemicalBook >?? ???? >GTP-GAMMA-S?????
GTP-GAMMA-S?????
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GTP-GAMMA-S????? ??
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- 2.68±0.1 g/cm3(Predicted)
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- -20°C (-15°C to -25°C)
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- ??(??)
- ?? ?? (pKa)
- 0.67±0.50(Predicted)
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- white
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- water: soluble
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| WGK ?? | - | ||
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| F ?????? | 10-21 |
GTP-GAMMA-S????? C??? ??, ??, ??
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GTP-γ-S has been used:- in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)
- in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα)
- to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants
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Guanosine 5′-O-(3-thiotriphosphate), tetralithium salt (GTP-γ-S) is a non-hydrolysable analog of GTP. It is an inhibitor of phosphodiesterase in photoreceptors.Biochem/physiol Actions
Guanosine 5′-O-(3-thiotriphosphate) (GTP-γ-S) activates guanine-nucleotide-binding proteins and is slowly hydrolyzed enzymatically. It inhibits guanosine triphosphatase (GTPases) more potently than guanosine triphosphate (GTP),GTP-GAMMA-S????? ?? ?? ? ???
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GTP-GAMMA-S????? ?? ??
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