4'-???-3'-?????????
|
|
4'-???-3'-????????? ??
- ???
- 117-121 °C(lit.)
- ?? ?
- 275.4℃
- ??
- 1.637
- ???
- 1.6090 (estimate)
- ???
- 120.4℃
- ?? ??
- Sealed in dry,Room Temperature
- ??? ??
- ??? ??
- ??
- ???? ?? ???
- BRN
- 2050098
- InChI
- InChI=1S/C8H6BrNO3/c1-5(11)6-2-3-7(9)8(4-6)10(12)13/h2-4H,1H3
- InChIKey
- YFVOFFKNHQTQQE-UHFFFAOYSA-N
- SMILES
- C(=O)(C1=CC=C(Br)C([N+]([O-])=O)=C1)C
- CAS ??????
- 18640-58-9(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
4'-???-3'-????????? C??? ??, ??, ??
??? ??
white to slightly yellow amorphous powder?? ??
4′-Bromo-3′-nitroacetophenone is an electron deficient acetophenone derivative.Synthesis
4'-Bromo-3'-nitroacetophenone is synthesised using 4'-Bromoacetophenone as a raw material by chemical reaction. The specific synthesis steps are as follows:To fuming nitric acid (200 mL), l-(4- bromophenyl)-l-propanone (1-1) (40 g, 0.20 mol) was added while keeping the inside temperature of mixture at 5 to 10 0C. The reaction solution was stirred at this temperature for 30 minutes and then poured into ice. The precipitate was collected by filtration, washed with distilled water (25 mL x 2) and re-crystallized from methanol to give 1-2 (18 g, 37percent yield). 1H NMR (500 MHz, CDCl3) δ 8.38 (IH, d, J= 2.0 Hz), 7.99 (IH, dd, J= 8.2 Hz, 2.0 Hz), 7.86 (IH, d, J= 8.2Hz), 3.01 (2H, q, J= 7.1Hz), 1.25 (3H, t, J= 7.1Hz) ppm; LC-MS (ESI): m/z 244.0 (M+H)+.
4'-???-3'-????????? ?? ?? ? ???
???
?? ??
4'-???-3'-????????? ?? ??
???( 197)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| DSHare Pharmaceutical Science Technology Co.Ltd. | +8613962878782 |
wei.zhu@dshare.com.cn | China | 42 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 |
sales@ansciepchem.com | CHINA | 4241 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49732 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29808 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9636 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 |
bd@blocksynth.com | China | 5660 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 7749 | 58 |
4'-???-3'-????????? ?? ??:
4'-???-3'-?????????
4'-Fluoro-3'-nitroacetophenone
4'-Bromoacetophenone
3-Nitrophenacylbromide
2-Bromo-4'-nitroacetophenone
2-BROMO-2'-NITROACETOPHENONE,-Bromo-2'-Nitroacetophenone
4-BROMO-3'-NITROBENZOPHENONE
3-nitro-4-bromopropiophenone
2-BROMO-5-NITROACETOPHENONE
5'-Bromo-2'-nitroacetophenone
3'-Bromo-4'-nitroacetophenone
A-BROMO-4-NITROACETOPHENONE HEXAMINE,α-Bromo-4-nitroacetophenone hexamine
2-Fluoro-3-Bromio-5-Nitro acetophenone
2'-Bromo-α-nitroacetophenone
Α-BROMO-P-NITROACETOPHENONE
2-bromo-1-(4-bromo-3-nitrophenyl)ethanone
3-(4-bromo-3-nitrophenyl)-3-oxopropanenitrile
4-BROMO-3,5-DINITROBENZOPHENONE