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??? ??? ???
?? ??:
6040-37-5
???:
???
???(??):
???
???:
Mutilin
???(??):
Mutilin;Tiamulin-impurity A;Lefamulin Impurity 14;Tiamulin EP Impurity A;Mutilin (Tiamulin EP Impurity A);(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethe;Tiamulin Hydrogen Fumarate EP Impurity A;(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyl-5,8-dihydroxy-4,6,9,10-tetramethyloctahydro-3a,9-propano-3aH-;3a,9-Propano-3aH-cyclopentacycloocten-1(4H)-one, 6-ethenyloctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-;(3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-Dihydroxy-4,7,9,12-tetramethyl-7-vinyloctahydro-4,9a-propanocyclopenta[8]annulen-3(3aH)-one (Mutilin (Tiamulin) Impurity)
CBNumber:
CB12703748
???:
C20H32O3
??? ??:
320.47
MOL ??:
6040-37-5.mol
MSDS ??:
SDS

??? ??

???
68-70 °C
?? ?
427.7±45.0 °C(Predicted)
??
1.09±0.1 g/cm3(Predicted)
?? ??
Hygroscopic, -20°C Freezer, Under inert atmosphere
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?????(??, ??? ??), ???????(?? ???)
?? ?? (pKa)
14.61±0.70(Predicted)
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  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
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?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.

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Mutilin is minor metabolite of the pleuromutilin family, originally isolated from Pleurotus mutilus. Mutilin is formed by hydrolysis of the hydroxyacetyl ester of pleuromutilin, and is a degradation product and in vivo metabolite of pleuromutilin. Interest in mutilin has focused on its potential as a substrate for generating unique metabolites via biosynthesis to provide a broader range of targets for semi-synthetic modification.

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