Bendamustine hydrochloride
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Bendamustine hydrochloride ??
- ???
- 149-151°C
- ?? ??
- room temp
- ???
- H2O: >30mg/mL
- ??? ??
- ??
- ??
- ???
- Merck
- 14,1034
- InChIKey
- ZHSKUOZOLHMKEA-UHFFFAOYSA-N
- CAS ??????
- 3543-75-7(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | T,Xn | ||
|---|---|---|---|
| ?? ???? ?? | 60-61-22-40 | ||
| ????? | 36-37 | ||
| ????(UN No.) | UN 2811 6.1 / PGIII | ||
| WGK ?? | 3 | ||
| RTECS ?? | DE1590000 | ||
| ?? ?? | 6.1 | ||
| ???? | III | ||
| HS ?? | 29339900 | ||
| ?? | LD50 (monohydrate) in mice, rats (mg/kg): 400-500, 200-300 orally; 80, 40 i.v. (Horn) |
Bendamustine hydrochloride C??? ??, ??, ??
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Pale Brown Crystals??
Bendamustine hydrochloride hydrate has been used as:- a chemotherapy agent for chronic lymphocytic leukemia (CLL) samples to monitor spliced and unspliced gene expression
- an inhibitor to E3 ubiquitin-protein ligase RNF3 (HOIP) in?matrix-assisted laser desorption ionization time-of-flight mass spectrometry?(MALDI-TOF) assay
- a cytotoxic chemotherapeutic drug in high-throughput screening to test interaction with BAY87-2243
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Bendamustine comprises 2-chloroethylamine alkylating group, a butyric acid side chain and a benzimidazole ring in its structure and is a nitrogen mustard. It is catabolized in the liver by the enzyme cytochrome P450 1A2 into γ hydroxyl-bendamustine and N-desmethyl-bendamustine.???? ??
Cytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those of purine analogs.Bendamustine hydrochloride ?? ?? ? ???
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Pentanoic acid, 5-[(2,4-dinitrophenyl)methylamino]-5-oxo-, methyl ester
Pentanoic acid, 5-[(2,4-dinitrophenyl)amino]-5-oxo-, methyl ester
isopropyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate
5-[??(2-?????)???]-1-??-1H-??????-2-?????????
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-hydroxyethyl)amino]-1-methyl-, 1-methylethyl ester
1-???-2.4-??????
5-[??(2-???????)???]-1-??-1H-??????-2-?????????
Methyl 4-(chloroformyl)butyrate
BendaMustine IMpurity C
2,4-???????
5-[??(2-??????)???]-1-??-1H-??????-2-?????????
N-??-2,4-???????
N1-??-4-???-o-?????
?? ??
Bendamustine hydrochloride ?? ??
???( 426)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 |
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| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 +86-18600796368 |
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| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
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| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19552 | 58 |
Bendamustine hydrochloride ?? ??:
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AMbroxoliMpurity
BroMo Prasugrel IMpurity
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid
5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
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